Results 41 to 50 of about 2,206,083 (299)

Unique Implantation Window as a Possible Reason of Embryo Transfer Failure. Retrospective Analysis

Clinical and Experimental Obstetrics & Gynecology, 2023
Background: To explore the predictive value of endometrial receptivity and pregnancy outcomes using pipelle biopsy examination during the luteal phase of the menstruation cycle in infertile women.
Oleksandra Kozyra, Mykhailo Medvediev, Andrea Tinelli   +2 more
doaj   +1 more source

Intrauterine interventions for women with two or more implantation failures: A systematic review and network meta-analysis

Frontiers in Endocrinology, 2022
ObjectiveTo compare the effectiveness of different intrauterine interventions for women with two or more unexplained implantation failures.DesignA systematic review and network meta-analysis of randomized controlled trials (RCTs).Patient(s)Women with two
Xin Hang Jin, Yang Li, Dan Li
doaj   +1 more source

Local versus general anesthesia for transcatheter aortic valve implantation (TAVR)- systematic review and meta-analysis [PDF]

, 2014
The hypothesis of this study was that local anesthesia with monitored anesthesia care (MAC) is not harmful in comparison to general anesthesia (GA) for patients undergoing Transcatheter Aortic Valve Implantation (TAVR).TAVR is a rapidly spreading ...
Webb, J, Reinthaler, M, Georg M Fröhlich, Marco Roffi, Olaf Wendler, Nevil Hutchinson, Markus Reinthaler, Duolao Wang, David Hildick-Smith, Wang, D, Hutchinson, N, Fröhlich, GM, John Webb, Pascal Meier, Alexandra J Lansky, Wendler, O, Hildick-Smith, D, Stefan Toggweiler, Lansky, AJ, Roffi, M, Meier, P, Toggweiler, S, Roffi, Marco, Wendler, Olaf, Webb, John, Lansky, Alexandra J, Wang, Duolao, Meier, Pascal, Hildick-Smith, David, Hutchinson, Nevil, Toggweiler, Stefan, Fröhlich, Georg M, Reinthaler, Markus   +32 more
core   +2 more sources

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

Melatonin Receptor 1B and Corticosteroid Receptor Polymorphisms in Infertile Women with Implantation Failure and Miscarriages

Frontiers in Bioscience-Landmark, 2023
Background: The development of assisted reproductive techniques has significantly improved fertility chances in many women, but recurrent implantation failure (RIF) and miscarriages (RM) might preclude successful pregnancy.
Ralitsa Robeva, Elena Marinova, Silvia Andonova, Georgi Nikolaev, Alexey Savov, Dobromir Tanev, Gueorgui Nikolov, Rossitza Konakchieva   +7 more
doaj   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw, Karishma Randhave, Ekta Anand, Ziang (Debbie) Song, Wangzhen Shen, Jing‐Qiong Kang   +5 more
wiley   +1 more source

Complementing Engel Classification: Postoperative Scalp EEG as an Objective Indicator in SEEG‐Guided Radiofrequency Thermocoagulation—A Seizure‐Onset Pattern‐Based Stratified Analysis—

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Stereoelectroencephalography‐guided radiofrequency thermocoagulation (SEEG‐RFTC) is a minimally invasive therapy for drug‐resistant focal epilepsy. However, the relationship between specific seizure‐onset patterns (SOPs), particularly low‐voltage fast activity (LVFA), and postoperative scalp EEG normalization remains inadequately ...
Yi‐qing Yang, Rui Zhang, Haiyan Ma, Lu Yang, Xuefeng Qu, Qiqi Chen, Yan Zhang   +6 more
wiley   +1 more source

Exploration of molecular features of PCOS with different androgen levels and immune-related prognostic biomarkers associated with implantation failure

Frontiers in Endocrinology, 2022
BackgroundPolycystic ovary syndrome (PCOS), the most common heterogeneous reproductive disease afflicting women of childbearing age, has been recognized as a chronic inflammatory disease recently.
Qinyu Gao, Qinyu Gao, Qinyu Gao, Cong Ma, Cong Ma, Cong Ma, Shuyu Meng, Guanxiong Wang, Guanxiong Wang, Guanxiong Wang, Qiong Xing, Qiong Xing, Qiong Xing, Yuping Xu, Yuping Xu, Yuping Xu, Xiaojin He, Xiaojin He, Xiaojin He, Tianjuan Wang, Tianjuan Wang, Tianjuan Wang, Yunxia Cao, Yunxia Cao, Yunxia Cao   +24 more
doaj   +1 more source

Extending Service Beyond Active Duty: Generalizability of Rheumatoid Arthritis Research Conducted Among US Veterans

Arthritis Care &Research, EarlyView.
Biomedical research involving US veterans continues to advance health care beyond the Veterans Health Administration. This is particularly true in rheumatoid arthritis (RA), where veteran‐centric research has uncovered novel insights into pathogenesis, risk factors, and disease manifestations, informing clinical care and research across both veteran ...
Austin M. Wheeler, Joshua F. Baker, Jennifer L. Barton, Maria I. Danila, Tate M. Johnson, Kamini Kuchinad, Kaleb Michaud, Amir A. Razmjou, J. Steuart Richards, Namrata Singh, Isaac D. Smith, Katherine D. Wysham, Grant W. Cannon, Bryant R. England, Amy Joseph, Deana Lazaro, Katherine P. Liao, Courtney Loecker, Andreas Reimold, Beth I. Wallace, Ted R. Mikuls   +20 more
wiley   +1 more source