Results 41 to 50 of about 206 (188)
Advanced Science, EarlyView.SLC25A13 is identified as an immunometabolic driver of triple‐negative breast cancer that sustains ferroptosis resistance and immune evasion through a STAT3–IFI6 circuit. Pharmacologic degradation of SLC25A13 restores ferroptosis sensitivity and enhances anti‐PD‐1 efficacy, highlighting a strategy to convert immune‐cold tumors into immunotherapy ...
Yingze Zhu +8 more
wiley +1 more source
Complicações dos implantes de mama: papel dos exames de imagem e principais sinais associados
Brazilian Journal of Health ReviewIntrodução: As próteses de mama vêm se tornando cada vez mais comuns, tanto no âmbito da reconstrução de mamas em mulheres pós-mastectomizadas quanto na abordagem estética de aumento. Apesar de serem um recurso importante para a cirurgia plástica, os implantes podem sofrer uma série de complicações, precoces ou tardias.
Ana Carolina Santos Lima +5 more
openaire +1 more source
Advanced Science, EarlyView.Inhibition of KDELR2 in a small fraction of tumor cells generates sustainable immunogenic cell death conditions within the tumor microenvironment. These conditions promote the regression of tumors in a T cell independent manner. During regression, macrophages prime T cells that subsequently provide systemic protection against recurrence. The potency of
Shakti P Pattanayak +6 more
wiley +1 more source
Advanced Science, EarlyView.Aberrant GALNT7‐mediated O‐GalNAcylation stabilizes TAZ to drive gallbladder cancer progression through a feed‐forward transcriptional loop. Structure‐based screening identifies Olaparib as a potent GALNT7 antagonist that disrupts this oncogenic axis, providing an immediate therapeutic strategy for this aggressive malignancy.
Peng Qiu +11 more
wiley +1 more source
Congenital Abnormalities of the Breast. A Case Report
Medisur, 2015 Normal breasts have a wide range of shapes and sizes varying according to cultural, racial, or other conditions, but it is clear that there are abnormalities related to the shape, size, number, location, and so on.
Elvira María Martínez Barreto +2 more
doaj +2 more sources
Advanced Science, EarlyView.This study established a high‐quality organoid biobank derived from 68 tumor sites across 50 Chinese patients, elucidated the drug sensitivity‐based molecular subtyping in breast cancer, and revealed a novel mechanism of drug resistance mediated by the FAK‐ACSL1 pathway.
Hao Xu +10 more
wiley +1 more source
Advanced Science, EarlyView.Hypoxia triggers a dual mechanism for BHLHE40 upregulation: reactive oxygen species (ROS)‐dependent post‐translational modification and hypoxia‐inducible factor (HIF)‐dependent transcriptional activation. Under hypoxic conditions, mitochondrial BHLHE40 accumulates and senses ROS via cysteine thiol oxidation and disulfide‐linked homodimer formation ...
Jia Liu +13 more
wiley +1 more source
Revista do Colégio Brasileiro de Cirurgiões, 2018 Objectives: to assess the degree of patient satisfaction after undergoing breast augmentation and compare three different, easy, inexpensive and universal methods of preoperative choice of breast implant volume.
RAFAEL DAIBERT DE SOUZA MOTTA +3 more
doaj +1 more source
Enfermedad asociada al implante de mama
, 2023 UCR::Vicerrectoría de Investigación::Sistema de Estudios de Posgrado::Salud::Especialidad en Cirugía Plástica Reconstructiva y ...
openaire +1 more source
Advanced Science, EarlyView.The Gela/decitabine/La2(CO3)3 colloidal (GDLC) hydrogel developed here could reverse the epigenetic silencing of the GSDME gene by the synergistic interaction between DAC and La3+, while concurrently activating caspase‐3, thus facilitating pyroptosis induction under the tumor microenvironment.
Yang Hong +6 more
wiley +1 more source