Results 191 to 200 of about 1,732,510 (272)
Estudio clínico e histológico del beta-fosfato tricálcico en la elevación del seno maxilar [PDF]
, 2008 García Méndez, Ángel María +4 more
core +1 more source
Epilepsia, EarlyView.Abstract Objective Focal cortical dysplasia (FCD) causes drug‐resistant epilepsy requiring presurgical evaluation. Invasive electroencephalographic (EEG) studies demonstrate that sleep modulates epileptic activity, including interictal epileptiform discharges (IEDs), fast oscillations (FOs) in the beta (14–40 Hz) and gamma (40–80 Hz) frequency bands ...
Marcel Heers +13 more
wiley +1 more source
Aplicaciones biomédicas del titanio v sus aleaciones [PDF]
, 1993 Gil, F.J., Planell Estany, Josep Anton
core +2 more sources
Epilepsia, EarlyView.Abstract Objective Current pharmacotherapy for temporal lobe epilepsy (TLE) is limited to symptomatic treatment and leaves approximately one third of patients with inadequate seizure control. Discovering disease‐modifying targets is an unmet clinical need. We have previously identified senescent cells (SCs) as one such target. Many drugs that eliminate
David J. McFall +3 more
wiley +1 more source
Epilepsia, EarlyView.Abstract Objective Pathogenic variants in the calcium/calmodulin‐dependent protein kinase II B gene (CAMK2B) have been associated with neurodevelopmental disorders, including epilepsy, yet the mechanisms underlying cortical dysfunction remain largely unclear.
Hiroki Mutoh +3 more
wiley +1 more source
Management of ring chromosome 20 syndrome: Narrative review and consensus recommendations
Epilepsia, EarlyView.Abstract Ring chromosome 20 (ring 20) is a rare genetic condition usually presenting as developmental and epileptic encephalopathy. The disease is caused by fusion of the long and short arms of chromosome 20. Patients are symptomatic even if there is no loss of genetic material.
Asma Khamis +8 more
wiley +1 more source
Epilepsia, EarlyView.Abstract Objective Memory problems are comorbid with temporal lobe epilepsy (TLE). Animal models of TLE reveal impairments in spatial firing fields of hippocampal place cells, providing a potential neural substrate for memory problems. Each subfield of the hippocampus carries out unique aspects of spatial memory, yet little is known about how ...
Brittney L. Boublil +4 more
wiley +1 more source
Epilepsia, EarlyView.On day 0 adult male and female rats were injected with Stable Substance P‐Saporin (SSP‐SAP) at 4 unilateral sites along the longitudinal axis of the dentate gyrus. Rats exhibited spontaneous electrographic and behavioral reactive seizures between days 4‐6. There was a progressive loss of CA1 and CA3 neurons and a progressive increase in astrocytes over
Srijal Gupta +4 more
wiley +1 more source
Epilepsia Open, EarlyView.Abstract Infantile epilepsy spasms syndrome (IESS), formerly known as infantile spasms or West Syndrome, is a severe epilepsy syndrome affecting about 3 in 10,000 newborns in the United States. Characterized by clusters of epileptic spasms, interictal hypsarrhythmia, and developmental delays, IESS has diverse causes, including structural‐metabolic ...
Kayla Vieira +5 more
wiley +1 more source
The multiple hit model of infantile and epileptic spasms: The 2025 update
Epilepsia Open, EarlyView.Abstract Objective Infantile and epileptic spasms syndrome (IESS) is a developmental and epileptic encephalopathy manifesting with epileptic spasms and poor neurodevelopmental outcomes. There is an urgent need for the development of more effective and tolerated therapies.
Aristea S. Galanopoulou +6 more
wiley +1 more source