Results 131 to 140 of about 15,148,604 (394)

Analysis of comprehensive genomic profiling of solid tumors with a novel assay for broad analysis in clinical diagnostics

Molecular Oncology, EarlyView.
In molecular cancer diagnostics, comprehensive genomic profiling (CGP) is going to replace the small NGS panels since it provides all clinically relevant somatic variants as well as genomic biomarkers with clinical value. Here, we compared two CGP assays and demonstrate that the choice for diagnostic implementation will depend on the specific ...
Guy Froyen, Pieter‐Jan Volders, Ellen Geerdens, Severine Berden, Joni Van der Meulen, Aaron De Cock, Stefanie Vermeire, Jacques Van Huysse, Marie de Barsy, Gabriela Beniuga, Wendy W. J. de Leng, Anne M. L. Jansen, Imke Demers, Zeliha Ozgur, Hendrikus Jan Dubbink, Ernst‐Jan M. Speel, Wilfred F. J. van IJcken, Brigitte Maes   +17 more
wiley   +1 more source

Effectiveness and safety of natural mineral water rich in magnesium and sulfates for the intestinal function

Медицинский совет, 2016
A randomized, placebo-controlled, double-blind trialObjective. The present randomized placebo-controlled double-blind trial was conducted to examine whether natural mineral water with a high content of magnesium sulfate and sodium sulfate (Donat Mg ...
Gordana Bote, Alyaz Chokh, Annegret Auinger   +2 more
doaj   +1 more source

CGP++ : A Modern C++ Implementation of Cartesian Genetic Programming [PDF]

The reference implementation of Cartesian Genetic Programming (CGP) was written in the C programming language. C inherently follows a procedural programming paradigm, which entails challenges in providing a reusable and scalable implementation model for complex structures and methods.
arxiv   +1 more source

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

Molecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane, Jérôme Ambroise, Cédric van Marcke, Mieke Van Bockstal, Martine Berlière, Christine Galant, Hélène Dano, Médina Lougué, Elena Benidovskaya, Guy Jerusalem, Vincent Bours, Claire Josse, Jérôme Thiry, Aurélie Daumerie, Caroline Bouzin, Cyril Corbet, François P. Duhoux   +16 more
wiley   +1 more source

Determinants of implementation of continuous glucose monitoring for patients with Insulin-Treated type 2 diabetes: a national survey of primary care providers

BMC Primary Care
Objectives To identify determinants of continuous glucose monitoring (CGM) implementation from primary care providers’ (PCPs’) perspectives and examine the associations of these determinants with both PCP intent to discuss CGM with eligible patients and ...
Varsha G. Vimalananda, Ben Kragen, Alison J. Leibowitz, Shirley Qian, Jolie Wormwood, Amy M. Linsky, Patricia Underwood, Paul R. Conlin, Bo Kim   +8 more
doaj   +1 more source

A Survey on Hardware Implementations of Elliptic Curve Cryptosystems [PDF]

arXiv, 2017
In the past two decades, Elliptic Curve Cryptography (ECC) have become increasingly advanced. ECC, with much smaller key sizes, offers equivalent security when compared to other asymmetric cryptosystems. In this survey, an comprehensive overview of hardware implementations of ECC is provided.
arxiv  

Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer

Molecular Oncology, EarlyView.
We used whole exome and RNA‐sequencing to profile divergent genomic and transcriptomic landscapes of microsatellite stable (MSS) and microsatellite instable (MSI) colorectal cancer. Alterations were classified using a computational score for integrative cancer variant annotation and prioritization.
Efstathios‐Iason Vlachavas, Konstantinos Voutetakis, Vivian Kosmidou, Spyridon Tsikalakis, Spyridon Roditis, Konstantinos Pateas, Ryangguk Kim, Kymberleigh Pagel, Stephan Wolf, Gregor Warsow, Antonia Dimitrakopoulou‐Strauss, Georgios N. Zografos, Alexander Pintzas, Johannes Betge, Olga Papadodima, Stefan Wiemann   +15 more
wiley   +1 more source

Implementation of Endomorphisms of the CAR Algebra [PDF]

Rev. Math. Phys. 7 (1995) 833-869, 1997
The implementation of non-surjective Bogoliubov transformations in Fock states over CAR algebras is investigated. Such a transformation is implementable by a Hilbert space of isometries if and only if the well-known Shale-Stinespring condition is met. In this case, the dimension of the implementing Hilbert space equals the square root of the Watatani ...
arxiv  

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

Molecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park, Jae Won Oh, Hyewon Chung, Jung Won Kwon, Yi Rang Na, Kwang Pyo Kim, Seung Hyeok Seok   +6 more
wiley   +1 more source

Conversion of the uniform CPA examination to a computer-based examination [PDF]

, 1999
https://egrove.olemiss.edu/aicpa_exam/1178/thumbnail ...
Joint AICPA/NASBA Computerization Implementation Committee
core   +1 more source