Results 51 to 60 of about 4,577,824 (243)

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Social Attributions from Faces: Determinants, Consequences, Accuracy, and Functional Significance [PDF]

, 2015
Since the early twentieth century, psychologists have known that there is consensus in attributing social and personality characteristics from facial appearance.
Mende-Siedlecki, Peter, Dotsch, Ron, Social-cognitive and interpersonal determinants of behaviour, Todorov, Alexander, Leerstoel Aarts, Olivola, Christopher Y, Olivola, C.Y., Mende-Siedlecki, P., Todorov, A.T., Dotsch, R.   +9 more
core   +1 more source

Accelerating the impact of artificial intelligence in mental healthcare through implementation science.

, 2022
BACKGROUND: The implementation of artificial intelligence (AI) in mental healthcare offers a potential solution to some of the problems associated with the availability, attractiveness, and accessibility of mental healthcare services.
Johansson, Jan, Nilsen, Per, Nilsen, Per,, Frideros, Micael,, Nygren, Jens, Schueller, Stephen, Svedberg, Petra, Schueller, Stephen,, Frideros, Micael, Johansson, Jan,, Nygren, Jens,, Svedberg, Petra,, Nygren, Jens M.,   +12 more
core   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Determinants of sustainable continuous improvement (Kaizen) implementation in Malaysian automotive part supplier SMEs [PDF]

, 2018
Globalization has caused many organizations to adapt themselves to the ever-changing business environment in order to sustain in this competitive market condition. Malaysian automotive part suppliers SMEs are also affected by the globalization. To remain
Mohd Ghazali, Maarof, Suhaila, Abdul Hamid, Sorooshian, Shahryar   +2 more
core   +3 more sources

Implementation of electronic prospective surveillance models in cancer care: a scoping review

Implementation Science, 2023
Background Electronic prospective surveillance models (ePSMs) for cancer rehabilitation include routine monitoring of the development of treatment toxicities and impairments via electronic patient-reported outcomes.
Christian J. Lopez, Kylie Teggart, Mohammed Ahmed, Anita Borhani, Jeffrey Kong, Rouhi Fazelzad, David M. Langelier, Kristin L. Campbell, Tony Reiman, Jonathan Greenland, Jennifer M. Jones, Sarah E. Neil-Sztramko   +11 more
doaj   +1 more source

Refining a taxonomy for guideline implementation: results of an exercise in abstract classification. [PDF]

, 2013
BACKGROUND: To better understand the efficacy of various implementation strategies, improved methods for describing and classifying the nature of these strategies are urgently required.
Danielle Mazza, Phillip Bairstow, Samantha Paubrey Chakraborty, Van Hecke, O, Kunnamo, Ilkka, Heather Buchan, Grech, C, Grech, Cathy, Buchan, Heather, Chakraborty, Samantha, Mazza, D, Kunnamo, I, Oliver Van Hecke, Cathy Grech, Ilkka Kunnamo, Mazza, Danielle, Buchan, H, Bairstow, P, Van Hecke, Oliver, Bairstow, Phillip, Chakraborty, SP   +20 more
core   +2 more sources

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Integrating Social Determinants of Health and Health Equity Into Canadian Health Public Practice : Environmental Scan

, 2011
National Collaborating Centre for Determinants of Health. (2010). Integrating Social Determinants of Health and Health Equity into Canadian Public Health Practice: Environmental Scan 2010. Antigonish, NS: National Collaborating Centre for Determinants of

core