Results 61 to 70 of about 4,577,824 (243)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Progress report 3 Thames River Implementation Committee

, 1981
This third TRIC Progress Report outlines the revised status of each of the recommendations since the time of the first Progress Report, provides an overview of the 1980/81 work program, and provides a program status update for the 1981/82 program.
Thames River Implementation Committee
core   +1 more source

The Consolidated Framework for Implementation Research (CFIR) User Guide: a five-step guide for conducting implementation research using the framework

Implementation Science
Background The Consolidated Framework for Implementation Research (CFIR) is a determinant framework that includes constructs from many implementation theories, models, and frameworks; it is used to predict or explain barriers and facilitators to ...
Caitlin M. Reardon, Laura J. Damschroder, Laura Ellen Ashcraft, Claire Kerins, Rachel L. Bachrach, Andrea L. Nevedal, Ariel M. Domlyn, Jessica Dodge, Matthew Chinman, Shari Rogal   +9 more
doaj   +1 more source

Integrating Social Determinants of Health and Health Equity Into Canadian Health Public Practice : Executive summary

, 2011
This is a summary of Integrating Social Determinants of Health and Health Equity Into Canadian Public Health Practice: Environmental Scan 2010.

core  

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Enhancing infant pain assessment and treatment: investigating barriers, facilitators, and implementation outcomes with the ImPaC Resource

Implementation Science Communications
Introduction The Implementation of Infant Pain Practice Change (ImPaC) Resource is a 7-step, multifaceted, web-based implementation strategy to improve pain assessment and treatment in Neonatal Intensive Care Units (NICUs).
Mariana Bueno, Kate Pearson, Melanie A. Barwick, Marsha Campbell-Yeo, Christine Chambers, Carole Estabrooks, Rachel Flynn, Sharyn Gibbins, Denise Harrison, Wanrudee Isaranuwatchai, Sylvie LeMay, Melanie Noel, Jennifer Stinson, Anne Synnes, Charles Victor, Janet Yamada, Shirine Riahi, Bonnie Stevens   +17 more
doaj   +1 more source

Middle managers’ role in implementing evidence-based practices in healthcare: a systematic review

Implementation Science, 2018
Background Middle managers are in a unique position to promote the implementation of evidence-based practices (EBPs) in healthcare organizations, yet knowledge of middle managers’ role in implementation and determinants (e.g., individual-, organizational-
Sarah Birken, Alecia Clary, Amir Alishahi Tabriz, Kea Turner, Rosemary Meza, Alexandra Zizzi, Madeline Larson, Jennifer Walker, Martin Charns   +8 more
doaj   +1 more source

Summary : Boosting Momentum : Applying Knowledge to Advance Health Equity_

, 2014
National Collaborating Centre for Determinants of Health. (2014). Summary: Boosting momentum: applying knowledge to advance health equity. Antigonish, NS: National Collaborating Centre for Determinants of Health, St. Francis Xavier University.

core  

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

A research agenda to advance the study of implementation mechanisms

Implementation Science Communications
Background Implementation science scholars have made significant progress identifying factors that enable or obstruct the implementation of evidence-based interventions, and testing strategies that may modify those factors. However, little research sheds
Cara C. Lewis, Hannah E. Frank, Gracelyn Cruden, Bo Kim, Aubyn C. Stahmer, Aaron R. Lyon, Bianca Albers, Gregory A. Aarons, Rinad S. Beidas, Brian S. Mittman, Bryan J. Weiner, Nate J. Williams, Byron J. Powell, MNoE Group   +13 more
doaj   +1 more source