Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
“Kick the Bucket!” – An activity for enhancing leadership and learning [PDF]
Presenters will share an easy-to-use activity for engaging participants in leadership theory and concepts. “Kick the Bucket!” offers application in a variety of settings.
Helms, Sarah Jo, Kaufman, Eric K.
core
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Jing Li,1,* Ya-Qi Liu,2,* Jia Song,3 Xu-Fang Huang,1 Mei-Fen Chen1 1Department of Nursing, The Fifth Hospital Affiliated to Wenzhou Medical University, Lishui Central Hospital, Lishui, Zhejiang, 323000, People’s Republic of China; 2School of ...
Li J, Liu YQ, Song J, Huang XF, Chen MF
doaj
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Learning Leadership: A Qualitative Study on the Differences of Student Learning in Online versus Traditional Courses in a Leadership Studies Program [PDF]
As online education offerings are extended to more students, organizations are increasingly interested in the effectiveness of online learning compared to a traditional classroom.
Amber Manning-Ouellette, +3 more
core +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
KEPEMIMPINAN ISLAMI (STUDI FENOMENOLOGI PADA KEPALA SEKOLAH SMA BATIK 1 SURAKARTA)
Islamic leadership of the current headmaster is a determinant of the success and progress of an educational institution in obtaining blessings and ridho of Allah swt. Allah swt has given the example of the best man as an example of good for all people as
Barra Bahtiar Aziz, Ahyar Yuniawan
doaj +1 more source
The effects of affect: How implicit facial expressions impact explicit projections of transformational leadership [PDF]
This study sought to explore the following questions: 1. Do a leader's facial expressions have an impact on students’ opinions of the leader? 2. Is there a relationship between universally accepted human facial expressions and leadership factors within
Hanks, Sarah +3 more
core
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source

