Results 101 to 110 of about 4,836,532 (286)
, 2018 At the turn of the century, society began to move from a more mechanistic understanding of leadership to a more ecological one. The ecological approach to leadership is characterized by collective decision-making, collaboration, shared leadership, and ...
Cletzer, D. Adam, Kaufman, Eric K.
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Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Progress report on implementation aspects of the Thames River Basin water management study [PDF]
, 1978 This progress report identifies the preliminary stance adopted by the Thames River Implementation Committee towards the 29 recommendations contained in the 1975 Thames River Basin Water Management Study and outlines the activities carried out by the ...
Thames River Implementation Committee
core +1 more source
Discover Health SystemsHealth systems depend on workforce capacity, role clarity, and leadership support to sustain implementation of complex, team-based service delivery models. Assertive Community Treatment (ACT) is an evidence-based intervention for individuals with serious
Andrew P. Herdsman
doaj +1 more source
Implementation Science, 2017 Background Leadership style and specific organizational climates have emerged as critical mechanisms to implement targeted practices in organizations.
Erick G. Guerrero +2 more
doaj +1 more source
Community Food Bank of Southern Arizona's Michael McDonald on Leadership
, 2016 Peer Reviewed by Christina R. Kalel / Edited by Dr. Brandy A. Brown and Romi C. WittmanThis paper analyzes Michael McDonald, a leader in the nonprofit sector in Tucson, Ariz., through the lens of leadership effectiveness.
Glockner, Erin
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The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Leadership tools for wicked problems [PDF]
, 2014 Leadership for the Greater Good is not easy to achieve. Many of the issues leaders face are so complex that they have been called ‘wicked problems’ – not in the sense of being evil, but because they seem almost intractable.
Samuel Wilson, John Fien
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