Results 101 to 110 of about 129,648 (279)

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

A COMPREHENSIVE LITERATURE REVIEW ON THE ROLE OF LEADERSHIP STYLES IN IMPLEMENTATION OF STRATEGIC PLANS IN MALAWI STATE-OWNED ENTERPRISES

open access: yesIJEBD (International Journal of Entrepreneurship and Business Development)
The development of strategic plans has become sort of a cliché in recent years. However, studies show that developing a strategic plan is way easier than implementing it.
Geofrey Joseph Mfuni
doaj   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

MANAGEMENT PERSONNEL LEADERSHIP POTENTIAL OF HIGHER EDUCATION INSTITUTIONS DEVELOPMENT

open access: yesУніверситети і лідерство, 2015
The article consists of theoretical analysis of the concept of «leadership potential» in connection to the concepts of «leadership» and «personal potential»; the components of the leadership potential are defined.
Nelia Lebid
doaj  

Ambidextrous leadership and innovation: a process perspective and an experimental approach

open access: yesHumanities & Social Sciences Communications
Ambidextrous leadership is a context-based combination of opening and closing leadership behaviors, and is thought to enhance both leader and employee behaviors in complex innovation processes.
Yiheng Xi, Li Zhou, Haiyan Wang
doaj   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

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