Results 161 to 170 of about 28,489,203 (383)

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Building health research infrastructure in Rwanda

The Lancet Global Health, 2014
Rwandan Research and Implementation Writing Group
doaj   +1 more source

RESEARCH ON TRAINING TRAINERS IN PROGRAM IMPLEMENTATION: AN INTRODUCTION AND FUTURE DIRECTIONS [PDF]

, 1995
Nancy A. Neef
openalex   +1 more source

THE DESIGN AND IMPLEMENTATION OF OLAP SYSTEM. CASE STUDY – UNIVERSITY RESEARCH [PDF]

The aim of this study is to show that multidimensional modelling of existing data in organizations, depending on the topics of interest of managers and multidimensional view of data.
Assoc. Prof. Carmen Radut Ph. D, Lect. Cristina Tenovici Ph. D, Prof. Georgeta Şoavă Ph. D   +2 more
core  

Purposeful Sampling for Qualitative Data Collection and Analysis in Mixed Method Implementation Research

Administration and Policy in Mental Health and Mental Health Services Research, 2015
L. Palinkas, S. Horwitz, Carla A Green, J. Wisdom, N. Duan, K. Hoagwood   +5 more
semanticscholar   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Highlighting the ethics of implementation research [PDF]

The Lancet Global Health, 2019
Luyckx, Valerie A, Reis, Andreas Alois, Maher, Dermot, Vahedi, Mahnaz   +3 more
openaire   +2 more sources

The ACCEPTance of automation: refining circulating tumor cells enumeration for improved metastatic colorectal cancer prognosis

Molecular Oncology, EarlyView.
This study highlights the potential of automated enumeration using the ACCEPT software to refine circulating tumor cell (CTC) detection in metastatic colorectal cancer (mCRC). The automated method demonstrates improved accuracy and reduced variability compared to the manual approach.
Michela De Meo, Marco Siringo, Alessandro Vici, Ann Zeuner, Orietta Gandini, Paola Gazzaniga, Chiara Nicolazzo   +6 more
wiley   +1 more source

The role of economics in the QUERI program: QUERI Series. [PDF]

Background: The United States (U.S.) Department of Veterans Affairs (VA) Quality Enhancement Research Initiative (QUERI) has implemented economic analyses in single-site and multi-site clinical trials.
Barnett, Paul G, Smith, Mark W
core   +1 more source