Results 151 to 160 of about 10,513,270 (364)

Health system performance on greenhouse gas emissions, climate change and development status in 38 OECD countries

open access: yesScientific Reports
Health systems must solve two climate-related problems simultaneously: mitigate their greenhouse gas emissions and adapt to additional patient loads associated with climate-induced demands for care from weather sequalae and vector-borne diseases.
Jeffrey Braithwaite   +5 more
doaj   +1 more source

The Maximal MAM, a Reasonable Implementation of the Maximal Strategy [PDF]

open access: yesarXiv, 2017
This note is about a reasonable abstract machine, called Maximal MAM, implementing the maximal strategy of the lambda-calculus, that is, the strategy that always produces a longest evaluation sequence.
arxiv  

Peripheral blood leukocyte signatures as biomarkers in relapsed ovarian cancer patients receiving combined anti‐CD73/anti‐PD‐L1 immunotherapy in arm A of the NSGO‐OV‐UMB1/ENGOT‐OV30 trial

open access: yesMolecular Oncology, EarlyView.
Using mass cytometry, we analyzed serial blood samples from patients with relapsed epithelial ovarian cancer (EOC) treated with oleclumab–durvalumab combination immunotherapy in the NSGO‐OV‐UMB1/ENGOT‐OV30 trial. Our analysis identified potential predictive, monitoring, and response biomarkers detectable through liquid biopsy. These findings facilitate
Luka Tandaric   +11 more
wiley   +1 more source

Context matters in implementation science: a scoping review of determinant frameworks that describe contextual determinants for implementation outcomes

open access: yesBMC Health Services Research, 2019
BackgroundThe relevance of context in implementation science is reflected in the numerous theories, frameworks, models and taxonomies that have been proposed to analyse determinants of implementation (in this paper referred to as determinant frameworks).
P. Nilsen, S. Bernhardsson
semanticscholar   +1 more source

Implementation of Open Science in Lithuania

open access: yesNordic Perspectives on Open Science, 2019
The number of open science policies being adopted in Europe by universities and research institutions is constantly increasing, however many European countries face difficulties while implementing open science practically. This publication reveals the Lithuanian landscape of open science policies and institutional involvement in open science practices.
openaire   +3 more sources

Analysis of comprehensive genomic profiling of solid tumors with a novel assay for broad analysis in clinical diagnostics

open access: yesMolecular Oncology, EarlyView.
In molecular cancer diagnostics, comprehensive genomic profiling (CGP) is going to replace the small NGS panels since it provides all clinically relevant somatic variants as well as genomic biomarkers with clinical value. Here, we compared two CGP assays and demonstrate that the choice for diagnostic implementation will depend on the specific ...
Guy Froyen   +17 more
wiley   +1 more source

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

open access: yesMolecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane   +16 more
wiley   +1 more source

Statistical versus symbolic parsing for captioned-information retrieval [PDF]

open access: yesarXiv, 1994
We discuss implementation issues of MARIE-1, a mostly symbolic parser fully implemented, and MARIE-2, a more statistical parser partially implemented. They address a corpus of 100,000 picture captions. We argue that the mixed approach of MARIE-2 should be better for this corpus because its algorithms (not data) are simpler.
arxiv  

Implementation science in psychogeriatrics [PDF]

open access: yesInternational Psychogeriatrics, 2020
Nancy A. Pachana, Nancy Pachana
openaire   +3 more sources

Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
We used whole exome and RNA‐sequencing to profile divergent genomic and transcriptomic landscapes of microsatellite stable (MSS) and microsatellite instable (MSI) colorectal cancer. Alterations were classified using a computational score for integrative cancer variant annotation and prioritization.
Efstathios‐Iason Vlachavas   +15 more
wiley   +1 more source

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