Results 51 to 60 of about 4,069,434 (300)

Seroincidence of SARS-CoV-2 infection prior to and during the rollout of vaccines in a community-based prospective cohort of U.S. adults

Scientific Reports
This study used repeat serologic testing to estimate infection rates and risk factors in two overlapping cohorts of SARS-CoV-2 N protein seronegative U.S. adults.
Denis Nash, Avantika Srivastava, Yanhan Shen, Kate Penrose, Sarah G. Kulkarni, Rebecca Zimba, William You, Amanda Berry, Chloe Mirzayi, Andrew Maroko, Angela M. Parcesepe, Christian Grov, McKaylee M. Robertson   +12 more
doaj   +1 more source

When complexity science meets implementation science: a theoretical and empirical analysis of systems change

BMC Medicine, 2018
Background Implementation science has a core aim – to get evidence into practice. Early in the evidence-based medicine movement, this task was construed in linear terms, wherein the knowledge pipeline moved from evidence created in the laboratory through
Jeffrey Braithwaite, Kate Churruca, Janet C. Long, Louise A. Ellis, Jessica Herkes   +4 more
doaj   +1 more source

Instrumentation issues in implementation science [PDF]

Implementation Science, 2014
Abstract Background Like many new fields, implementation science has become vulnerable to instrumentation issues that potentially threaten the strength of the developing knowledge base. For instance, many implementation studies report findings based on instruments that do not have established psychometric properties.
Martinez, Ruben G, Lewis, Cara C, Weiner, Bryan J   +2 more
openaire   +2 more sources

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Combining Theory and Practice in the Teaching of Science Institutions: A Collaborative Program between the City University of New York and the American Museum of Natural History [PDF]

, 2000
The National Science Education Standards contain several mandates that share the use of alternative and creative experiences in the teaching of science at all levels.
Espinoza, F.
core   +1 more source

The “D&I Bridge”: introducing a teaching tool to define the D, the I, and the why

Implementation Science Communications
Interest in learning dissemination and implementation (D&I) science is at an all-time high. As founding faculty and fellows of a new center focused on D&I science, we have found that non-specialist researchers and newcomers to D&I science often express ...
Sara J. Becker, Kira DiClemente-Bosco, Kelli Scott, Sarah A. Helseth, Zabin Patel-Syed, Dennis H. Li   +5 more
doaj   +1 more source

Systems resilience in the implementation of a large-scale suicide prevention intervention: a qualitative study using a multilevel theoretical approach

BMC Health Services Research, 2023
Background Resilience, the capacity to adapt and respond to challenges and disturbances, is now considered fundamental to understanding how healthcare systems maintain required levels of performance across varying conditions.
Louise A Ellis, Yvonne Zurynski, Janet C Long, Robyn Clay-Williams, Eline Ree, Mitchell Sarkies, Kate Churruca, Fiona Shand, Chiara Pomare, Maree Saba, Cecilie Haraldseid-Driftland, Jeffrey Braithwaite   +11 more
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

The Reality of Uncertainty in Mental Health Care Settings Seeking Professional Integration: A Mixed-Methods Approach

International Journal of Integrated Care, 2018
Introduction: Uncertainty is a common experience in the complex adaptive health system, particularly amongst mental health professionals structured for the delivery of integrated care.
Chiara Pomare, Louise A. Ellis, Kate Churruca, Janet C. Long, Jeffrey Braithwaite   +4 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source