Results 71 to 80 of about 1,033,408 (309)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Implementation science: why should we care?

Journal of the Medical Library Association
There is a 17-year gap between the publication of research which proves an intervention is  efficacious and effective and the implementation of that same intervention into practice [1].
Frances Chu
doaj   +1 more source

The Reality of Uncertainty in Mental Health Care Settings Seeking Professional Integration: A Mixed-Methods Approach

International Journal of Integrated Care, 2018
Introduction: Uncertainty is a common experience in the complex adaptive health system, particularly amongst mental health professionals structured for the delivery of integrated care.
Chiara Pomare, Louise A. Ellis, Kate Churruca, Janet C. Long, Jeffrey Braithwaite   +4 more
doaj   +1 more source

Systems resilience in the implementation of a large-scale suicide prevention intervention: a qualitative study using a multilevel theoretical approach

BMC Health Services Research, 2023
Background Resilience, the capacity to adapt and respond to challenges and disturbances, is now considered fundamental to understanding how healthcare systems maintain required levels of performance across varying conditions.
Louise A Ellis, Yvonne Zurynski, Janet C Long, Robyn Clay-Williams, Eline Ree, Mitchell Sarkies, Kate Churruca, Fiona Shand, Chiara Pomare, Maree Saba, Cecilie Haraldseid-Driftland, Jeffrey Braithwaite   +11 more
doaj   +1 more source

Part 8: Education, implementation, and teams: 2015 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science with Treatment Recommendations

, 2015
Current evidence demonstrates considerable variability in cardiac arrest survival in and out of hospital and, therefore, substantial opportunity to save many more lives.1–3 The Formula for Survival4 postulates that optimal survival from cardiac arrest ...
Nadkarni, Vinay M., Duff, J., Jon C. Rittenberger, Lang, Eddy, Lang, E., Aaron J. Donoghue, Koenraad G. Monsieurs, Iwami, Taku, Billi, John E., Leary, M., Steven C. Brooks, Judith C. Finn, Ming-Ju Hsieh, Greif, R., Yeung, J., Bhanji, F., Cheng, A., Billi, John E, Elaine Gilfoyle, Lockey, A., Matthew Huei-Ming Ma, Andrew Lockey, Janet E. Bray, Robert Frengley, Finn, J., Dana P. Edelson, Lockey, Andrew, Robert Greif, Mary E. Mancini, Vinay M. Nadkarni, Fischer, H., Huei-Ming Ma, Matthew, Eddy Lang, Greif, Robert, Nadkarni, V., Monsieurs, K., David A. Kloeck, Taku Iwami, Iwami, T., Bhanji, Farhan, Bigham, Blair, Mancini, Mary E., Brooks, S., Theresa M. Olasveengen, McNeil, Mary Ann, Jan Breckwoldt, Bray, Janet, Adam Cheng, Finn, Judith C, Patrick Ko, Traci A. Wolbrink, Edelson, D., Schultz, R., Mancini, M., John E. Billi, Hsieh, M., Olasveengen, T., Zuzana Triska, Mancini, Mary E, Breckwoldt, J., Jonathan P. Duff, Robert D. Schultz, Dion Stub, McNeil, M., Rittenberger, J., Nadkarni, Vinay M, Stub, D., Yang, C., Frengley, Robert, Koenraad Monsieurs, Donoghue, A., Joyce Yeung, Kloeck, D., Frengley, R., Finn, Judith C., Blair Bigham, Henrik Fischer, Bigham, B., Wolbrink, T., Gilfoyle, E., Monsieurs, Koen, Billi, J., Monsieurs, Koenraad, Ma, Matthew Huei-Ming, Mary Ann McNeil, and on behalf of the Education, Implementation, and Teams Chapter Collaborators, Ma, M., Chih-Wei Yang, Ko, P., Triska, Z., Farhan Bhanji, Marion Leary   +91 more
core   +1 more source

Instrumentation issues in implementation science [PDF]

Implementation Science, 2014
Abstract Background Like many new fields, implementation science has become vulnerable to instrumentation issues that potentially threaten the strength of the developing knowledge base. For instance, many implementation studies report findings based on instruments that do not have established psychometric properties.
Martinez, Ruben G, Lewis, Cara C, Weiner, Bryan J   +2 more
openaire   +2 more sources

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Adapting the 2022 WHO verbal autopsy tool for use in Lagos State, Nigeria: insights from the LVASA-SRS project

BMC Research Notes
Objective Accurate and routine cause-of-death data are essential for health planning, yet many low- and middle-income countries lack comprehensive systems for such data, resulting in undocumented maternal and perinatal deaths.
Adeyemi Okunowo, Uchenna Gwacham-Anisiobi, Ndubuisi Ezumezu, Hameed Adelabu, Adedoyin Ogunyemi, Teniola Lawanson, Brenda Isikekpei, Bosede B. Afolabi, Aduragbemi Banke-Thomas   +8 more
doaj   +1 more source

Organisational change in hospitals: a qualitative case-study of staff perspectives

BMC Health Services Research, 2019
Background Organisational change in health systems is common. Success is often tied to the actors involved, including their awareness of the change, personal engagement and ownership of it.
Chiara Pomare, Kate Churruca, Janet C. Long, Louise A. Ellis, Jeffrey Braithwaite   +4 more
doaj   +1 more source

Implementing contingency management for stimulant use in opioid treatment programs: protocol of a type III hybrid effectiveness-stepped-wedge trial

Implementation Science, 2023
Background Contingency management (CM) is an evidence-based intervention for stimulant use and is highly effective in combination with medication for opioid use disorder.
Sara J. Becker, Kira DiClemente-Bosco, Kelli Scott, Tim Janssen, Sarah M. Salino, Fariha N. Hasan, Kimberly R. Yap, Bryan R. Garner   +7 more
doaj   +1 more source