Results 91 to 100 of about 31,672,605 (212)

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Primary science in Malaysia: the implementation of a new curriculum [PDF]

open access: yes
This thesis investigates the implementation of the science curriculum in Malaysian primary schools. The study is concerned primarily with teachers' pedagogical content knowledge as a crucial determinant of teaching performance in implementing the new ...
Yunus, Hashimah Mohd.
core  

Implementation Science in Health Care

open access: yes, 2017
Implementation science in health care comprises over 30 years of rich and varied activity that has developed, refined, and applied implementation science concepts, theories, and research approaches.
Alison B. Hamilton, Brian S. Mittman
core   +1 more source

Diagnosis and Roadmap for an Open Science Policy in Argentina [PDF]

open access: yes, 2022
General aim of this document: To make a diagnosis of the implementation of Law 26.899 (2013) on Open Access Repositories in light of the new context proposed by the UNESCO Open Science Recommendation (2021), to promote the opening of Argentine science ...
Ministry of Science, Technology and Innovation-MINCYT, Open Science and Citizens Science Advisory Committee
core  

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Strategy for soil and water management in the Thames River Basin [PDF]

open access: yes, 1982
This report presents a summary of the Thames River Implementation Committee program and discusses the key program recommendations related to policy, community education, land use management and conservation practices.Ontario Ministry of the ...
Thames River Implementation Committee
core   +1 more source

Factor selection in configurational comparative analysis – guidance for implementation researchers

open access: yesImplementation Science Communications
Background Configurational comparative methods (CCMs) are designed for the systematic comparison of case data to identify necessary and sufficient conditions for an outcome.
Laura Caci   +3 more
doaj   +1 more source

The goldilocks effect: the rhythms and pace of hospital life

open access: yesBMC Health Services Research, 2018
Background While we have made gains in understanding cultures in hospitals and their effects on outcomes of care, little work has investigated how the pace of work in hospitals is associated with staff satisfaction and patient outcomes.
Jeffrey Braithwaite   +3 more
doaj   +1 more source

Implementation science themes.

open access: yes, 2015
Implementation science themes.
Haq Nawaz (63419)   +13 more
core   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

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