Results 71 to 80 of about 221,505 (251)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

“My, you have a way of making me do things I don’t normally do.” The examination of the narrative (Un)Reliability of Joe Goldberg from You by Caroline Kepnes [PDF]

open access: yesPolish Journal of English Studies
Ever since Wayne C. Booth named the phenomenon of unreliability in narrative fiction, multiple attempts have been made to deepen the knowledge regarding its theoretical scope and practical implementation, resulting in two different approaches to its ...
Paula Sadkowska
doaj  

Castle Richmond, The Famine, and the Critics

open access: yesCahiers Victoriens et Edouardiens, 2003
Despite the fact that the narrator of Trollope’s Castle Richmond argues that the potato famine of 1845-51 served the beneficent purpose of reforming Irish agriculture, the novel should not be read as the Malthusian tract, inartistically yoked to a pallid
Jane Nardin
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

The Darkness in Umairoh

open access: yesBuletin Al-Turas, 2018
This research aims to find information about gender issues exploited by the author in The Jakarta Post short story ascribed by Yanusa Nugroho entitled Umairoh. The objectives of the research are 1. To investigate how women are described and positioned in
Hasnul Insani
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Die funksie van Elihu (Job 32-37) in die boek Job

open access: yesVerbum et Ecclesia, 1995
The function of Elihu (Job 32-37) in the book of Job. The Elihu speeches (Job 32-37) in the design of the book of Job are usually evaluated either totally redundant or literary fitting and functional.
H. Viviers
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

"Another game in vew": the representation of the poet in The Faerie Queene

open access: yesRevista Alicantina de Estudios Ingleses, 1989
Many recent critics of The Faerie Queene have established an artificial distinction between the narrator of The Faerie Queene and Spenser, one which posits an olympian detachment of the author from the work, and of both from the historical circumstances ...
García Landa, José Ángel
doaj   +1 more source

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