Results 101 to 110 of about 641,662 (279)
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
EHV Converter Station State Identification Technology Based on Cyber-physical Integration
Journal of Harbin University of Science and TechnologyDue to the wide range of data sources ， high collection density ， diverse measurement devices and complex communication protocols in the EHV converter station system，it is difficult for the existing technology to accurately ...
XIAO Yaohui +7 more
doaj +1 more source
Neurobiology of Disease, 2006 Alzheimer's disease (AD) is characterized neuropathologically by neuritic plaques (NPs), and neurofibrillary tangles (NFTs). So far, the following key issues are not yet answered to the disease: (1) the accumulation degrees of three Aβ variants, and tau ...
Xin-Wen Zhou +9 more
doaj +1 more source
Testing for Codependence of Non-Stationary Variables [PDF]
, 2010 We analyze non-stationary time series that do not only trend together in the long run, but restore the equilibrium immediately in the period following a deviation.
Trenkler, Carsten, Weber, Enzo
core
Molecular Oncology, EarlyView.Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
THE ESSENCE OF THE CONCEPT «SUBTEXT»: THEORETICAL ASPECTS
Записки з українського мовознавства, 2016 The article is devoted to the studying of subtext as the means of the influence in mass media discourse. It is told in detail about the problem of the term's meaning and its definition. The types of information in the texts of different functional genres
Ю. А. Снігоцька
doaj +1 more source
Hedging tranches index products : illustration of model dependency [PDF]
In this paper, index tranches'properties and several hedging strategies are discussed. Model risk and correlation risk are analysed through the study of the efficiency of several factor based copula models, like the Gaussian, the double-t and the double ...
Dominique Guegan, Julien Houdain
core
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
A Solution to the Time-Scale Fractional Puzzle in the Implied Volatility
Fractal and Fractional, 2017 In the option pricing literature, it is well known that (i) the decrease in the smile amplitude is much slower than the standard stochastic volatility models and (ii) the term structure of the at-the-money volatility skew is approximated by a power-law ...
Hideharu Funahashi, Masaaki Kijima
doaj +1 more source
Correlation still does not imply causation [PDF]
The Lancet Psychiatry, 2016 Charles, Ksir, Carl L, Hart
openaire +2 more sources