Results 81 to 90 of about 119,536 (302)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Implied Volatilities of Caps: a Gaussian approach. [PDF]

open access: yes
Implied volatilities of interest rate derivatives present some distinctive features, like the inverse relation with the underlying rates and the humped or decreasing shape of their term structure.
Flavio Angelini, Stefano Herzel
core  

Role and place of the inherent and implied president powers in the constitutional governance system of the United States of America

open access: yesRUDN Journal of Law, 2010
The article covers the problem of constitutional law in the United States of America, connected with the presence of considerable scope of inherent and implied powers of the US president.
P A Kucherenko
doaj  

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Correlated implied volatility with jump and cross section of stock returns

open access: yes, 2015
I derive the option-implied volatility allowing for nonzero correlation between price jump and diffusive risk to examine the information content of implied diffusive, jump risks and their implied covariance in the cross-sectional variation of future ...
Ze-To, S.
core   +1 more source

THE CORRELATION OF A RELATIONSHIP WITH INDIVIDUAL STAKEHOLDERS OF LIFELONG LEARNING INSTITUTIONS – THE CASE OF CROATIA

open access: yesCroatian Operational Research Review, 2012
In this paper, public and/or nonprofit institutions of lifelong learning in Croatia have been analysed. The main issue of the research is the correlation between the established relationships with the individual target groups of lifelong learning ...
Zoran Mihanović   +2 more
doaj  

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Forecasting volatility and correlation : the role of option implied measures

open access: yes, 2012
Forecasts of volatility and correlation are important inputs into many practical financial problems. Broadly speaking, there are two ways of generating forecasts of these variables.
Coleman-Fenn, Christopher Andrew
core  

COORDINATES OF A RISK MANAGEMENT PROJECT [PDF]

open access: yesChallenges of the Knowledge Society, 2013
High risk – high benefit: a well-known correlation both in the economic field and in the day-to-day life. Another correlation, on which this article is based: large project – numerous participants – increased risks and other malfunctions.
ALEXANDRU OLTEANU   +1 more
doaj  

Empirical Evidence on Time-Varying Hedging Effectiveness of Emissions Allowances under Departures from the Cost-of-Carry Theory

open access: yesDiscrete Dynamics in Nature and Society, 2013
Under departures from the cost-of-carry theory, traded spot prices and conditional volatility disturbed from futures market have significant impacts on futures price of emissions allowances, and then we propose time-varying hedge ratios and hedging ...
Kai Chang
doaj   +1 more source

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