Results 61 to 70 of about 119,536 (302)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

The four-point correlation function of the energy-momentum tensor in the free conformal field theory of a scalar field

open access: yesEuropean Physical Journal C: Particles and Fields, 2020
We present an explicit momentum space computation of the four-point function of the energy-momentum tensor in 4 spacetime dimensions for the free and conformally invariant theory of a scalar field.
Mirko Serino
doaj   +1 more source

Multifunctionality does not imply that all functions are positively correlated [PDF]

open access: yesProceedings of the National Academy of Sciences, 2014
The recent publication by Bradford et al. (1) argues that indices of ecosystem multifunctionality—the simultaneous performance of multiple ecosystem functions (2)—are only useful if all component functions “respond to community change in a positive correlated fashion.” We contend that this argument fundamentally misinterprets the concept of ecosystem ...
Jarrett Byrnes   +5 more
openaire   +4 more sources

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Is implied correlation worth calculating? Evidence from foreign exchange options and historical data [PDF]

open access: yes
Implied volatilities, as derived from option prices, have been shown to be useful in forecasting the subsequently observed volatility of the underlying financial variables.
Christian Walter, Jose A. Lopez
core  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Foreign exchange option and returns based correlation forecasts: evaluation and two applications [PDF]

open access: yes
We compare option-implied correlation forecasts from a dataset consisting of over 10 years of daily data on over-the-counter (OTC) currency option prices to a set of return-based correlation measures and assess the relative quality of the correlation ...
Castrén, Olli, Mazzotta, Stefano
core  

Thermal out-of-time-order correlators, KMS relations, and spectral functions

open access: yesJournal of High Energy Physics, 2017
We describe general features of thermal correlation functions in quantum systems, with specific focus on the fluctuation-dissipation type relations implied by the KMS condition. These end up relating correlation functions with different time ordering and
Felix M. Haehl   +4 more
doaj   +1 more source

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