Results 61 to 70 of about 404,538 (313)

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

J. Stephan Lürman, Japan-Import, Frankfurt a. M., Weserstraße 4

J. STEPHAN LÜRMAN, JAPAN-IMPORT, FRANKFURT A. M., WESERSTRASSE 4 J. Stephan Lürman, Japan-Import, Frankfurt a. M., Weserstraße 4 ( -
J. Stephan Lürmann Japan Import
core   +3 more sources

Empirical analysis of import demand behavior of least developed countries [PDF]

This paper examines the long-run stability of import demand function in Least Developed Countries (LDC) using recently developed panel cointegration techniques.
Shigeyuki Hamori, Yoichi Matsubayashi
core   +2 more sources

Differential Biological Effects of Trifolium pratense Extracts—In Vitro Studies on Breast Cancer Models

Antioxidants
The increasing popularity of herbal supplements emphasizes the need of scientific data regarding their health benefits and possible toxicological concerns.
Lucian Albulescu, Alexandru Suciu, Mihaela Neagu, Cristiana Tanase, Sevinci Pop   +4 more
doaj   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

The Import of Vitalism

Science, 1911
n ...
openaire   +3 more sources

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

The Importance of Variable Importance

, 2022
32 ...
openaire   +2 more sources

p53 stabilization: the importance of nuclear import [PDF]

Cell Death & Differentiation, 2010
In response to cellular stress, the p53 tumor suppressor protein is stabilized as a result of inactivation of ubiquitin-mediated degradation. The p53 protein rapidly accumulates in the nucleus, where it functions as a transcription factor. Although the regulation of p53 stability has been studied extensively, the subcellular compartment in which p53 ...
openaire   +2 more sources