Results 41 to 50 of about 2,087,092 (260)

Protocol for quantifying miRNA trafficking across the endosomal membrane

open access: yesFEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh   +2 more
wiley   +1 more source

Estimated Import Demand Function for Pakistan: A Disaggregated Analysis

open access: yesJISR Management and Social Sciences & Economics, 2015
The theme of the study was to estimate the elasticity of aggregated and selected disaggregated import demand function with relative prices and income for Pakistan from 1982 to 2011 on annual data.
Imran Ullah Khan Marwat
doaj  

Threonine 348 regulates the subcellular localization of PTEN

open access: yesFEBS Open Bio, EarlyView.
Thr348 in the C2 domain is a key contributor to PTEN subcellular localization. The PTEN350 fragment and PTENA4 accumulated in the nucleus, whereas PTENK13R,A4 predominantly localized to the plasma membrane. In contrast, substitution of Thr348 with Asp (T348D) disrupted these characteristic localization patterns, resulting in predominant cytoplasmic ...
Takashi Kato, Suzu Tanaka, Miyu Ohashi
wiley   +1 more source

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

open access: yesFEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez   +4 more
wiley   +1 more source

Indonesia Export, Import, and Demand for Domestic Commodities under Economics Liberalisation

open access: yesEconomic Journal of Emerging Markets, 2011
The aim of this research is to identify the behaviour of export, import and domestic commodities demand in liberalization era both in the long run and the short run.
Andi Irawan
doaj   +5 more sources

An aggregate import demand function for Australia: a cointegration approach [PDF]

open access: yes
This paper investigates the relationship among quantity of imports, relative import prices and real GDP in the aggregate import demand function for Australia during the period 1959Q3Ã’2006Q3.
Riaz Shareef, Vu Tran
core  

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

open access: yesFEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Analysis of Rice Imports in Indonesia: AIDS approach

open access: yesJournal of Economics, Business & Accountancy Ventura, 2018
Rice is a staple food for Indonesian households. After achieving self-sufficiency of rice in 1984, Indonesia still had to import rice because the domestic rice consumption always exceeded the domestic rice production.
Agus Widarjono
doaj   +1 more source

Seafood Import Demand in the Caribbean Region [PDF]

open access: yes
Cointegration analysis and an Error Correction Model are used to estimate aggregate seafood import demand functions for selected Caribbean countries. The results show that seafood import demand is price elastic.
Jolly, Curtis M., Nguyen, Giap V.
core  

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

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