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Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
The Effects of the Underground Economy on Demand for Imports of Intermediate, Consumption and Capital Goods in Iran [PDF]
This paper investigates the effects of underground economy on the Iran’s imports demand for intermediate, consumption and capital goods during 1971-2011.
hamidReza horry +2 more
doaj
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Empirical analysis of import demand behavior of least developed countries [PDF]
This paper examines the long-run stability of import demand function in Least Developed Countries (LDC) using recently developed panel cointegration techniques.
Shigeyuki Hamori, Yoichi Matsubayashi
core +2 more sources
Measuring accuracy and computational capacity trade-offs in an hourly integrated energy system model
Improving energy system modeling capabilities can directly affect the quality of applied studies. However, some modeling trade-offs are necessary as the computational capacity and data availability are constrained.
Amirhossein Fattahi +4 more
doaj +1 more source
RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour +2 more
wiley +1 more source
The impact of oil prices on import demand in an oil-rich country: a multisectoral Bayesian approach
This study examines Qatar’s import demand function across sixteen economic sectors, employing a Bayesian approach to estimate the price, income and oil price elasticities. The findings reveal that import demand is predominantly price inelastic (−0.079 to
Ozcan Ozturk, Miranda Canga
doaj +1 more source
Malate Transport and Metabolism in Nitrogen-Fixing Legume Nodules
Legumes form a symbiosis with rhizobia, a soil bacterium that allows them to access atmospheric nitrogen and deliver it to the plant for growth. Biological nitrogen fixation occurs in specialized organs, termed nodules, that develop on the legume root ...
Nicholas J. Booth +3 more
doaj +1 more source
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source

