Results 31 to 40 of about 656,585 (296)

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

IMPORT SUBSTITUTION IN RUSSIA AS DEVELOPMENT FACTOR IN GLOBAL CHALLENGES PERIOD OF 2017–2019

open access: yesМодернизация, инновация, развитие, 2018
Purpose: objectives of research: 1) Justification of a new role of import-substituting strategy as factor of large-scale import-substituting industrial revolution in the Russian Federation, an economic development driving force; 2) Confirmation of ...
N. I. Komkov, N. N. Bondareva
doaj   +1 more source

'Import Preservation' in Lieu of Import Substitution [PDF]

open access: yesSSRN Electronic Journal, 2015
Import substitution in the Russian industry shows obvious signs of a slowdown. Both comparative results of actually implemented import substitution quarter-on-quarter and plans of enterprises for the last quarter of the current year attest to this.
openaire   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

Mitochondrial Protein Import [PDF]

open access: yes, 1987
The role of nucleoside triphosphates (NTPs) in mitochondrial protein import was investigated with the precursors of N. crassa ADP/ATP carrier, F1-ATPase subunit β, F0-ATPase subunit 9, and fusion proteins between subunit 9 and mouse dihydrofolate ...
Pfanner, Nikolaus   +2 more
core   +1 more source

Normative base of import substitution [PDF]

open access: yes, 2019
Импортозамещение является одной из стратегических задач развития экономики РФ. Важным инструментом реализации импортозамещения в России выступает стандартизация.
Грибов, В. В.   +5 more
core   +1 more source

The Influence of Import Substitution on Regional Positioning in the System of International Economic Relations [PDF]

open access: yesЭкономика региона, 2018
The purpose of the research is to substantiate what kind of influence the import substitution has on the positioning of different types of regions in the system of international economic relations.
Elena Leonidovna Andreeva   +3 more
doaj   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

open access: yesFEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana   +5 more
wiley   +1 more source

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