Results 41 to 50 of about 195,046 (305)

PRINCIPLES OF IMPORT SUBSTITUTION REGARDING DRUGS

open access: yesФармакоэкономика, 2015
This articles is devoted to major principles of import substitution regarding drugs within the scope of restriction lists at various levels of the health care system.
Alana Viktorovna Dzaneva   +2 more
doaj   +1 more source

Algorithm of Estimating Import-Substitution Based on Costs – Output Tables

open access: yesВестник Российского экономического университета имени Г. В. Плеханова, 2021
The article studies problems and prospects of managerial decisions dealing with the process of import-substitution of certain products and puts forward the method of raising its efficiency.
N. A. Moiseev, B. A. Akhmadeev
doaj   +1 more source

Development Trends and Economic Assessment of the Integration Processes on the Metals Market [PDF]

open access: yes, 2015
In the present paper, reasons for the increased interest in industrial policy in both developed and developing countries are explained. The systematisation of the results of the development of Russian industry from 1989 to 2014 showed a lack of ...
Makarov, E. V., Romanova, O. A.
core   +2 more sources

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

Structural index of import substitution and its testing under the impact of shocks on the Russian economy

open access: yesВекторы благополучия: экономика и социум
To date, there are a number of approaches to the quantitative assessment of import substitution, which, however, do not affect the structural nature of its initiation in the long term.
S.A. Zhironkin , E.A. Taran
doaj   +1 more source

Import substitution Impact on Growth of Production of Mineral Products and Metallurgy: shortTerm and long-Term Forecasting of basic sectors of the National Economy

open access: yesФинансы: теория и практика, 2023
The purpose of the study is to identify ways of short- and medium-term development of mineral production and metallurgy in the Russian Federation in the context of the policy of sanctions based on economic and mathematical modeling.
E. A. Fedorova   +3 more
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

open access: yesAdvanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio   +11 more
wiley   +1 more source

Information Support Tasks in Import Substitution and Conversion

open access: yesInformaciâ i Innovacii, 2020
The article gives data of the problem of import substitution and conversion to the reindustrialization of the Russian economy on a new technological basis as a part of a comparative analysis by industry.
Е. Yu. Dmitrieva, О. V. Suintuirenko
doaj   +1 more source

The incomplete transformation of institutions of economic policy: from clientelism to competition? [PDF]

open access: yes, 2013
Economic policy in Turkey has gone through significant amount of transformation in the last three decades. While Turkey used to be a closed economy governed by an import-substitution industrialization strategy, starting in the early 1980s it went through
Atiyas, İzak, Atiyas, Izak
core  

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