Results 41 to 50 of about 27,072 (294)
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source
MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis
FEBS Open Bio, EarlyView.MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss +7 more
wiley +1 more source
Cognitive and Neuroimaging Divergence Between Juvenile and Adult FUS Amyotrophic Lateral Sclerosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by progressive motor neuron degeneration. Fused in sarcoma (FUS)‐associated juvenile ALS (jALS) represents a distinct and aggressive subgroup with rapid deterioration and poor prognosis.
Alexandra V. Jürs +7 more
wiley +1 more source
Финансы: теория и практика, 2023 The purpose of the study is to identify ways of short- and medium-term development of mineral production and metallurgy in the Russian Federation in the context of the policy of sanctions based on economic and mathematical modeling.
E. A. Fedorova +3 more
doaj +1 more source
'Import Preservation' in Lieu of Import Substitution [PDF]
SSRN Electronic Journal, 2015 Import substitution in the Russian industry shows obvious signs of a slowdown. Both comparative results of actually implemented import substitution quarter-on-quarter and plans of enterprises for the last quarter of the current year attest to this.
openaire +1 more source
IMPORT SUBSTITUTION OF MEASURING EQUIPMENT [PDF]
, 2023 Импортозамещение средств измерительной техники играет важную роль в современной экономике. Оно способствует снижению зависимости от импорта и развитию отечественного производства.
Gribov, V. +5 more
core
Векторы благополучия: экономика и социумTo date, there are a number of approaches to the quantitative assessment of import substitution, which, however, do not affect the structural nature of its initiation in the long term.
S.A. Zhironkin , E.A. Taran
doaj +1 more source
Algorithm of Estimating Import-Substitution Based on Costs – Output Tables
Вестник Российского экономического университета имени Г. В. Плеханова, 2021 The article studies problems and prospects of managerial decisions dealing with the process of import-substitution of certain products and puts forward the method of raising its efficiency.
N. A. Moiseev, B. A. Akhmadeev
doaj +1 more source
β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Advanced Biology, Volume 9, Issue 3, March 2025.Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio +11 more
wiley +1 more source