Results 41 to 50 of about 656,585 (296)

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

THE MECHANISM OF IMPLEMENTATION OF THE POLICYOF IMPORT SUBSTITUTION IN THE ARKHANGELSK REGION

open access: yesМодернизация, инновация, развитие, 2016
In modern conditions of development of the world economy and the processes of globalization increasingly raises the question of the independence of the region from products that are necessary for the viability of the population purchased from third-party
N. Didenko, A. Kuzaeva
doaj   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

open access: yesFEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh   +2 more
wiley   +1 more source

Factors that Necessitate Import Substitution in Russia and Mechanisms for Its Implementation

open access: yesЭкономика и управление, 2019
The problem of import substitution in Russia, which has been repeatedly brought up during the period of relative economic stability and high international prices on energy carriers, has become particularly crucial due to the exacerbated international ...
Aleksey V. Abramov, Aleksey V. Titov
doaj  

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

open access: yesFEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez   +4 more
wiley   +1 more source

Import substitution policy effectiveness assessment in industry: methodological tools [PDF]

open access: yes, 2015
Russia's transition to non-oil development model generates a new vector of industrial policy, focused on the implementation of projects of import substitution.
Chernova Olga A.   +2 more
core   +1 more source

Foreign-domestic substitution, import penetration and CGE modelling

open access: yes, 2021
Foreign-domestic substitution elasticities (the so-called ‘Armington elasticities’) determine the degree of competitiveness in demand between similar products produced in different countries and are key parameters in a variety of numerical models of ...
Verikios, George   +2 more
core   +1 more source

Actual issues of tax policy of Russia in the conditions of import replacement

open access: yesУченые записки Российской академии предпринимательства, 2021
Materials and methods. The article examines the approaches of modern Russian scientists to the definition of the current state and prospects for the development of import substitution in Russia; the possible directions of tax incentives for innovative ...
R. B. Rubinov, A. A. Iskandaryan
doaj  

Cognitive and Neuroimaging Divergence Between Juvenile and Adult FUS Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by progressive motor neuron degeneration. Fused in sarcoma (FUS)‐associated juvenile ALS (jALS) represents a distinct and aggressive subgroup with rapid deterioration and poor prognosis.
Alexandra V. Jürs   +7 more
wiley   +1 more source

Development of Mechanisms for the Identification of Priority Industries for Import Substitution in Russia

open access: yesЭкономика и управление, 2019
This study is dedicated to developing a mechanism for the identification of priority industries for import substitution in Russia. Aim. This study aims to structure the elements of the proposed mechanism for the identification of priority industries for ...
Anton S. Evtyukhin
doaj  

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