Results 111 to 120 of about 2,693,397 (282)
Metamodel-based importance sampling for structural reliability analysis
, 2011 Structural reliability methods aim at computing the probability of failure of systems with respect to some prescribed performance functions. In modern engineering such functions usually resort to running an expensive-to-evaluate computational model (e.g.
Deheeger, F., Dubourg, V., Sudret, B.
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
MathematicsThe application of machine learning and artificial intelligence to solve scientific challenges has significantly increased in recent years. A remarkable development is the use of Physics-Informed Neural Networks (PINNs) to solve Partial Differential ...
Hui Li +4 more
doaj +1 more source
Importance sampling-accelerated simulation of full-spectrum backscattered diffuse reflectance. [PDF]
Biomed Opt Express, 2023 Mao J, Ling Y, Xue P, Su Y.
europepmc +1 more source
Group Importance Sampling for Particle Filtering and MCMC
, 2018 Bayesian methods and their implementations by means of sophisticated Monte Carlo techniques have become very popular in signal processing over the last years.
Camps-Valls, G., Elvira, V., Martino, L.
core
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Pareto Smoothed Importance Sampling
, 2019 Importance weighting is a general way to adjust Monte Carlo integration to account for draws from the wrong distribution, but the resulting estimate can be noisy when the importance ratios have a heavy right tail.
Gabry, Jonah +4 more
core
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Robust Multiple Importance Sampling with Tsallis φ-Divergences. [PDF]
Entropy (Basel), 2022 Sbert M, Szirmay-Kalos L.
europepmc +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source