Results 51 to 60 of about 7,538,728 (303)

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen   +23 more
wiley   +1 more source

Sampling using a ‘bank’ of clues [PDF]

open access: yes, 2010
An easy-to-implement form of the Metropolis Algorithm is described which, unlike most standard techniques, is well suited to sampling from multi-modal distributions on spaces with moderate numbers of dimensions (order ten) in environments typical of ...

core   +2 more sources

Approximate Methods for Maximum Likelihood Estimation of Multivariate Nonlinear Mixed-Effects Models

open access: yesEntropy, 2015
Multivariate nonlinear mixed-effects models (MNLMM) have received increasing use due to their flexibility for analyzing multi-outcome longitudinal data following possibly nonlinear profiles.
Wan-Lun Wang
doaj   +1 more source

Stochastic Enumeration with Importance Sampling [PDF]

open access: yesMethodology and Computing in Applied Probability, 2018
Many hard problems in the computational sciences are equivalent to counting the leaves of a decision tree, or, more generally, summing a cost function over the nodes. These problems include calculating the permanent of a matrix, finding the volume of a convex polyhedron, and counting the number of linear extensions of a partially ordered set.
openaire   +2 more sources

Solid Pseudopapillary Neoplasm of the Pancreas in Children and Adolescents: Expert Recommendations

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Solid pseudopapillary neoplasm of the pancreas (SPN) is a rare low‐grade malignant exocrine pancreatic tumor, mostly discovered during the second decade of life in females, with a very good prognosis, provided microscopically complete surgical excision is achieved.
Sabine Irtan   +18 more
wiley   +1 more source

Ovarian Sex Cord Stromal Tumors in Children and Adolescents—The European Standard Clinical Practice Recommendations

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT As part of the European Cooperative Study Group for Paediatric Rare Tumours initiative, we developed standard clinical practice guidelines for ovarian sex cord stromal tumors, based on comprehensive national and international cohort analyses, literature review, and a final expert consensus conference.
Dominik T. Schneider   +15 more
wiley   +1 more source

Halton Sampling for Image Registration Based on Mutual Information

open access: yes, 2008
Mutual information is a widely used similarity measure for aligning multimodal medical images. At its core, it relies on the computation of a discrete joint histogram, which itself requires image samples for its estimation.
Michel Bierlaire   +5 more
core   +1 more source

Fully Bayesian Experimental Design for Pharmacokinetic Studies

open access: yesEntropy, 2015
Utility functions in Bayesian experimental design are usually based on the posterior distribution. When the posterior is found by simulation, it must be sampled from for each future dataset drawn from the prior predictive distribution.
Elizabeth G. Ryan   +2 more
doaj   +1 more source

Application of quasi-Monte Carlo and importance sampling to Monte Carlo-based fault tree quantification for seismic probabilistic risk assessment of nuclear power plants

open access: yesMechanical Engineering Journal, 2023
The significance of probabilistic risk assessments (PRAs) of nuclear power plants against external events was re-recognized after the Fukushima Daiichi Nuclear Power Plant accident.
Kotaro KUBO   +5 more
doaj   +1 more source

Infant Embryonal CNS Tumors: Molecular Insights and Treatment Considerations for Contemporary Pediatric Neuro‐Oncology

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Embryonal tumors comprise the majority of malignant central nervous system (CNS) neoplasms diagnosed in children under 3 years of age. Compared with their counterparts in older children, these tumors exhibit distinct molecular biology and a more aggressive clinical phenotype, while their management is complicated by the heightened ...
Sudarshawn Damodharan   +3 more
wiley   +1 more source

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