Results 51 to 60 of about 7,538,728 (303)
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen +23 more
wiley +1 more source
Sampling using a ‘bank’ of clues [PDF]
An easy-to-implement form of the Metropolis Algorithm is described which, unlike most standard techniques, is well suited to sampling from multi-modal distributions on spaces with moderate numbers of dimensions (order ten) in environments typical of ...
core +2 more sources
Approximate Methods for Maximum Likelihood Estimation of Multivariate Nonlinear Mixed-Effects Models
Multivariate nonlinear mixed-effects models (MNLMM) have received increasing use due to their flexibility for analyzing multi-outcome longitudinal data following possibly nonlinear profiles.
Wan-Lun Wang
doaj +1 more source
Stochastic Enumeration with Importance Sampling [PDF]
Many hard problems in the computational sciences are equivalent to counting the leaves of a decision tree, or, more generally, summing a cost function over the nodes. These problems include calculating the permanent of a matrix, finding the volume of a convex polyhedron, and counting the number of linear extensions of a partially ordered set.
openaire +2 more sources
Solid Pseudopapillary Neoplasm of the Pancreas in Children and Adolescents: Expert Recommendations
ABSTRACT Solid pseudopapillary neoplasm of the pancreas (SPN) is a rare low‐grade malignant exocrine pancreatic tumor, mostly discovered during the second decade of life in females, with a very good prognosis, provided microscopically complete surgical excision is achieved.
Sabine Irtan +18 more
wiley +1 more source
ABSTRACT As part of the European Cooperative Study Group for Paediatric Rare Tumours initiative, we developed standard clinical practice guidelines for ovarian sex cord stromal tumors, based on comprehensive national and international cohort analyses, literature review, and a final expert consensus conference.
Dominik T. Schneider +15 more
wiley +1 more source
Halton Sampling for Image Registration Based on Mutual Information
Mutual information is a widely used similarity measure for aligning multimodal medical images. At its core, it relies on the computation of a discrete joint histogram, which itself requires image samples for its estimation.
Michel Bierlaire +5 more
core +1 more source
Fully Bayesian Experimental Design for Pharmacokinetic Studies
Utility functions in Bayesian experimental design are usually based on the posterior distribution. When the posterior is found by simulation, it must be sampled from for each future dataset drawn from the prior predictive distribution.
Elizabeth G. Ryan +2 more
doaj +1 more source
The significance of probabilistic risk assessments (PRAs) of nuclear power plants against external events was re-recognized after the Fukushima Daiichi Nuclear Power Plant accident.
Kotaro KUBO +5 more
doaj +1 more source
ABSTRACT Background Embryonal tumors comprise the majority of malignant central nervous system (CNS) neoplasms diagnosed in children under 3 years of age. Compared with their counterparts in older children, these tumors exhibit distinct molecular biology and a more aggressive clinical phenotype, while their management is complicated by the heightened ...
Sudarshawn Damodharan +3 more
wiley +1 more source

