Results 131 to 140 of about 59,978 (299)
Wild Poliovirus Importation, Central African Republic
Emerging Infectious Diseases, 2013 Ionela Gouandjika-Vasilache +6 more
doaj +1 more source
Advanced Science, EarlyView.. ABSTRACT Neural presbycusis disrupts auditory timing and speech perception, yet its molecular basis remains poorly understood. This study identifies Cntn2 as the Ranvier's nodal molecule significantly downregulated in aged auditory nerves. Cntn2 heterozygous knockout (Cntn2+/−) mice showed elevated auditory brainstem response thresholds and prolonged
Penghui Chen +8 more
wiley +1 more source
Advanced Science, EarlyView.. ABSTRACT Neuroinflammation driven by microglial activation is a defining feature of Alzheimer's disease (AD), yet the molecular mechanisms sustaining this proinflammatory state remain unclear. Here, we identify the deubiquitinase OTUD7B as a critical regulator of microglial activation and AD pathology.
Luyao Li +15 more
wiley +1 more source
Advanced Science, EarlyView.Using single‐cell transcriptomic and epigenomic profiling, researchers mapped microglial dysfunction across the lifespan of db/db mice. The authors uncovered a nonlinear microglial remodeling featuring early inflammatory priming, a mid‐stage transcriptional inflection, and late dysfunction.
Jizhou Zhang +6 more
wiley +1 more source
Automated treatment of electronic resources in the Scientific Information Service at CERN [PDF]
, 2001 We describe the automatic method of importation of meta data, developed in the Scientific Information Service, SIS, at CERN. The program, called Uploader, allows importation into the CERN library databases of bibliographic records and full text documents
Jerdelet, Jocelyne +2 more
core
Advanced Science, EarlyView.Magnetomechanical neuromodulation using magnetic nanodiscs enables remote activation of neurons. In a hemiparkinsonian mouse model, alternating magnetic fields actuate the nanodiscs to generate torque that opens mechanosensitive ion channels within the subthalamic nucleus, thereby modulating basal ganglia motor circuitry.
Anouk Wolters +12 more
wiley +1 more source
Geo: Geography and EnvironmentElectronic waste (e‐waste) can be defined as discarded or obsolete electronic and electrical equipment that is no longer functional or desired. Globally, e‐waste poses significant problems and threats to the environment, society and health of the ...
Richard Kwame Adom +1 more
doaj +1 more source
Possible Influence of Importation of Hawaiian Sugar on Beet-Sugar Production in the United States
A statement of the production, importation, and consumption of sugar in the United States, with a discussion of the possibilities and limitation of sugar production in Hawaii and the effect of the free importation of Hawaiian sugar upon the sugar-beet ...
Office of the Secretary
core +1 more source
Synchronization‐Dissipation in the Cardiorespiratory System
Advanced Science, EarlyView.By modeling central nervous coupling and viscoelastic interactions in the cardiorespiratory system we show that synchronization produces a 10% gain in cardiac efficiency in humans. It is surmised that respiratory sinus arrhythmia improves cardiac pumping efficiency by reducing dynamic stress and power dissipation in the pulmonary vasculature.
Joshua R. Border +3 more
wiley +1 more source
Certification of importation signed by Benjamin Lincoln [PDF]
Benjamin Lincoln certifies the importation of one Cask of Wine containing fifty-four gallons, by William J. Nath. Hooper in the Joanna Zinnia, an American Vessel, from Bourdeaux, dated October 20, 1804.https://digitalcommons.wofford.edu/littlejohnmss ...
Lincoln, Barnabas
core +1 more source