Results 51 to 60 of about 56,626 (243)

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Framework evaluation for first importation event.

, 2022
Framework evaluation for first importation event.
Lucia Mullen (12530372), Doreen Tuhebwe (716005), Steven Ssendagire (9969354), Rhoda K. Wanyenze (8614842), Alex Riolexus Ario (5662199), Christina Potter (10175024), Susan Babirye (12530375), Rebecca Nuwematsiko (9106417), Jennifer B. Nuzzo (10587599)   +8 more
core   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Estimating probabilities of malaria importation in southern Mozambique through modelling P. falciparum genomics and mobility patterns

eLife
Imported malaria is a critical obstacle to achieving elimination in low transmission settings, but importation classification tools combining human mobility and parasite genomics are lacking.
Arnau Pujol, Arlindo Chidimatembue, Clemente da Silva, Simone Boene, Henriques Mbeve, Pau Cisteró, Carla García-Fernández, Arnau Vañó-Boira, Dário Tembisse, José Inácio, Glória Matambisso, Fabião Luis, Nelo Ndimande, Humberto Munguambe, Lidia Nhamussua, Wilson Simone, Andrés Aranda-Díaz, Manuel García-Ulloa, Neide Canana, Maria Tusell, Júlia Montaña, Laura Fuente-Soro, Khalid Ussene Bapu, Maxwell Murphy, Bernardete Rafael, Eduard Rovira-Vallbona, Caterina Guinovart, Bryan Greenhouse, Sonia Maria Enosse, Francisco Saúte, Pedro Aide, Baltazar Candrinho, Alfredo Mayor   +32 more
doaj   +1 more source

Epidemiologic Situation on Cholera in the World, CIS Countries and Russia. Prognosis

Проблемы особо опасных инфекций, 2010
Epidemiologic situation on cholera in the world, CIS countries and Russia has been evaluated for the period of 2000-2009. The last decade (2000-2009) is characterized by the on-going large epidemics and outbreaks of cholera in the countries of Africa and
Yu. M. Lomov, E. A. Moskvitina
doaj   +1 more source

Tariff Equivalent of Technical Barriers to Trade with Imperfect Substitution and Trade Costs, November 2005 [PDF]

, 2005
The price-wedge method yields a tariff-equivalent estimate of technical barriers to trade (TBT). An extension of this method accounts for imperfect substitution between domestic and imported goods and incorporates recent findings on trade costs.

core  

Threonine 348 regulates the subcellular localization of PTEN

FEBS Open Bio, EarlyView.
Thr348 in the C2 domain is a key contributor to PTEN subcellular localization. The PTEN350 fragment and PTENA4 accumulated in the nucleus, whereas PTENK13R,A4 predominantly localized to the plasma membrane. In contrast, substitution of Thr348 with Asp (T348D) disrupted these characteristic localization patterns, resulting in predominant cytoplasmic ...
Takashi Kato, Suzu Tanaka, Miyu Ohashi
wiley   +1 more source

Prohibition of importation, manufacturing and sale of Smokeless Tobacco (SLT) products: what is the Global Scenario?

, 2018
Background Over the past 10 years, the WHO FCTC has served as a powerful tool to initiate, support, and advance national and global tobacco control efforts.
Deepika Saraf
core   +1 more source