Results 201 to 210 of about 490,177 (259)

Qualitative Risk Assessment of Infectious Agents Associated with Canine Importation into Canada, 2023-2024. [PDF]

Emerg Infect Dis
Leung VM, Chiasson J, Patterson V, Narasimhan A, Anderson MEC, Epp T, Fernandez-Prada C, Gordon EW, Rocheleau JP, Stull JW, Vachon M, Weese S, Clow KM.   +12 more
europepmc   +1 more source

SAV1 in Cooperation With FKBP52 Participates in Implantation

Advanced Science, EarlyView.
The MST‐SAV1 complex modulates FKBP52 phosphorylation to fine‐tune PR activity, ensuring timely uterine transition to receptivity under estrogen signaling for implantation. Stromal SAV1 scaffolds MST1/2‐mediated FKBP52 phosphorylation via noncanonical Hippo to promote PR activity.
Yuhan Shao, Yafang Lu, Zhaoyu Jia, Junxiang Ren, Ziyi Ge, Xinyu Liu, Hui Zhao, Zi‐Jiang Chen, Junhao Yan, Wei Wang, Jia Yuan   +10 more
wiley   +1 more source

CE Mark Is Not Enough: Medical Device Safety in African Healthcare Systems. [PDF]

Med Devices (Auckl)
Matovu B, Ssekitoleko RT, Kamuhanda S, Odokonyero K.   +3 more
europepmc   +1 more source

Nuclear IDH3A Drives Transcriptional Programs in Melanoma via the YBX1–JUN/FOS Axis

Advanced Science, EarlyView.
Genomic amplification drives aberrant nuclear localization of IDH3A in melanoma. Independent of its canonical metabolic activity, nuclear IDH3A cooperates with YBX1 to activate the c‐JUN/c‐FOS transcriptional program, while NONO facilitates its nuclear localization.
Juan Ran, Yanchun Fang, Shengming Ruan, Juling Wang, Songbai Liu, Yuan Mao, Dongsheng Hou, Yanping Wang, Zi Ye, Qiong Li, Daoxiang Zhang   +10 more
wiley   +1 more source

Cluster of imported cutaneous leishmaniasis due to <i>Leishmania major</i> among travellers returning from central Tunisia, France, October 2025 to May 2026. [PDF]

Euro Surveill
Andreoletti M, Guemas E, Charpentier E, Fillaux J, Valentin A, Chauvin P, Berry A, Iriart X.   +7 more
europepmc   +1 more source

A Tumor‐Boundary Niche Enriched for PD‐1+CD8+T Cells and BTLA+B Cells Drives Resistance to Immunotherapy in NSCLC

Advanced Science, EarlyView.
A spatial niche composed of BTLA+B cells and CD8+T cells is enriched at the tumor boundary in non‐small cell lung cancer. Within this specialized niche, BTLA+B cells act as a dominant source of IL‐6, upregulating PD‐1 on CD8+T cells via STAT3 signaling.
Jiajuan Wu, Shiying Guo, Leilei Lv, Guiqin Fan, Yu Shen, Qiuxia Qu, Cheng Chen   +6 more
wiley   +1 more source

Imported Furuncular Myiasis Due to <i>Cordylobia anthropophaga</i>: A Case Highlighting the Role of Ultrasonography and Morphological Confirmation. [PDF]

Pathogens
Adamczuk J, Sikorska K, Czupryna P, Borawski K, Matwiejuk M, Malla H, Jebessa M, Moniuszko-Malinowska A.   +7 more
europepmc   +1 more source

Acid‐Responsive Nanobot‐Integrated Core‐Shell Microneedles Reprogram the Degenerative Annulus Fibrosus Microenvironment Through Epigenetic Suppression of Ferroptosis

Advanced Science, EarlyView.
An acid‐responsive core‐shell microneedle system normalizes the degenerative annulus fibrosus microenvironment by consuming pathological H+, generating O2, and providing NIR‐amplified redox buffering. Mechanistically, it epigenetically suppresses ferroptosis via DNMT3A‐dependent methylation of the ATF3 promoter, relieving ATF3‐mediated repression of ...
Lu Tan, Yan Zheng, Yue Lan, Zhuo Cheng, Siya Wang, Changqing Li, Yanqiu Wang, Minghan Liu   +7 more
wiley   +1 more source

Trends in Age, Weight, and Health Status among Cynomolgus Macaques (Macaca fascicularis) Imported into the United States during 2014-2023. [PDF]

J Am Assoc Lab Anim Sci
Swisher S, Bowden SE, Carroll A, Latzer M, Taetzsch S, Laughlin ME, Pieracci E.   +6 more
europepmc   +1 more source