Results 51 to 60 of about 102,206 (317)

Permutation importance: a corrected feature importance measure [PDF]

open access: yesBioinformatics, 2010
Abstract Motivation: In life sciences, interpretability of machine learning models is as important as their prediction accuracy. Linear models are probably the most frequently used methods for assessing feature relevance, despite their relative inflexibility.
André Altmann   +3 more
openaire   +3 more sources

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Identification of the plant mitochondrial OrfX protein: A mass spectrometry approach

open access: yesFEBS Letters, EarlyView.
The mitochondrial genome of plants contains an open reading frame, orfx, which encodes a rare protein that has so far escaped mass spectrometric detection. The protein resembles the c‐subunit of bacterial twin‐arginine‐motif‐dependent protein translocases (TatC).
Matthias Döring   +3 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Imported Items Found at the Uvek Site (Accidental Finds Kept at the Saratov Regional Museum of Local Lore)

open access: yesПоволжская археология, 2013
A collection of 396 imported items found on the Uvek fortified settlement site as accidental discoveries is discussed in the article. Among them, the majority of ceramic products are mostly ceremonial utensils.
Kubankin Dmitriy A.   +1 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

The Role of Critical Raw Material Imports in Shaping Economic Competitiveness within the European Union

open access: yesRomanian Economic Journal
Critical raw materials (CRMs) represent essential resources for several strategic sectors in the European Union and strategies are necessary to reduce dependence on imports and improve the efficiency of their use. The European Union is facing significant
Ramona Iulia Dieaconescu   +3 more
doaj   +1 more source

Spatial differentiations of trade links between Ukraine and Czechia

open access: yesActa Universitatis Carolinae Geographica, 2019
The purpose of this article is to examine the current status of economic ties between Ukraine and Czechia, identify main trends in the contemporary commodity trade between Ukraine and Czechia, and to investigate the regional structure of Ukraine’s ...
Volodymyr Lazhnik   +2 more
doaj   +1 more source

Importance tempering

open access: yesStatistics and Computing, 2008
16 pages, 2 tables, significantly shortened from version 4 in response to referee comments, to appear in Statistics and ...
Robert B. Gramacy   +2 more
openaire   +2 more sources

Home - About - Disclaimer - Privacy