Results 61 to 70 of about 553,918 (315)

M. Kh. Reutern and Tariff Reform in Russia

open access: yesŒconomia, 2014
This article discusses the content and context of the Memorandum on Tariff Reform in Russia by M. Reutern that is presented in an accompanying article.
Vincent Barnett
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Steel imports [PDF]

open access: yes
Steel industry and trade ; Free ...
Hang-Sheng Cheng, Laura Leete
core  

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

RESULTS AND PROSPECTS FOR THE DEVELOPMENT OF THE BELARUSIAN-CHINESE COOPERATION THE SILK ROAD ECONOMIC BELT

open access: yesNauka ta progres transportu, 2020
Purpose. The most ambitious economic and geopolitical project at present is the New Silk Road initiative, which can radically modify transport and cash flows in Eurasia and around the world.
O. A. Khodoskina   +2 more
doaj   +1 more source

The Impact of Domestic and Import Prices on U.S. Lamb Imports: A Production System Approach [PDF]

open access: yes
As U.S. lamb imports increased relative to domestic production, and the relative share of chilled to frozen lamb imports increased, importers of chilled lamb have become less responsive to domestic and import prices, while the direct opposite is the case
Hahn, William F.   +2 more
core   +1 more source

p53 stabilization: the importance of nuclear import [PDF]

open access: yesCell Death & Differentiation, 2010
In response to cellular stress, the p53 tumor suppressor protein is stabilized as a result of inactivation of ubiquitin-mediated degradation. The p53 protein rapidly accumulates in the nucleus, where it functions as a transcription factor. Although the regulation of p53 stability has been studied extensively, the subcellular compartment in which p53 ...
openaire   +2 more sources

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

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