Results 51 to 60 of about 8,510 (275)

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

open access: yesFEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai   +8 more
wiley   +1 more source

Are Impossible Worlds Trivial? [PDF]

open access: yes, 2013
Theories of content are at the centre of philosophical semantics. The most successful general theory of content takes contents to be sets of possible worlds.
Jago, Mark
core  

The filed of biography in the Ismaili Literature.

open access: yesمجلة العلوم و آفاق المعارف, 2023
Talking about digital text or digital literature is a controversial conversation because of the intellectual differences and conflicts that the topic carries, and a great controversy taking place in the critical and literary arena.
maatougui chahinez, kaddour. tifouri
doaj   +1 more source

Comprehensive Characterization of 98 Chinese Cases of Genetic Creutzfeldt‐Jakob Disease With T188K Mutation

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterize the demographic, clinical, and laboratory features of the Chinese patients of genetic Creutzfeldt‐Jakob disease with T188K variant (T188K‐gCJD), the most common subtype of genetic prion diseases (gPrDs) in China. Methods In this nationwide retrospective study, data from 98 genetically confirmed T188K‐gCJD patients ...
Chun‐Jie Li   +11 more
wiley   +1 more source

The Ontology of Impossible Worlds [PDF]

open access: yes, 2008
The best arguments for possible worlds. as states of affairs furnish us with equally good arguments for impossible worlds of the same sort. I argue for a theory of impossible worlds on which the impossible worlds correspond to maximal inconsistent ...
David A. Vander Laan
core  

Information or Evidence? Abandoning Imaginary Worlds for Blockchains in Health Technology Assessment

open access: yesINNOVATIONS in Pharmacy, 2018
Commentaries published in INNOVATIONS in Pharmacy over the past 2 years have made the case that, as a basis for formulary decision making, the construction of imaginary modeled worlds fails to meet the standards of normal science. As such, they should be
Paul Langley
doaj   +1 more source

The digital poem between the poles of creativity and reception

open access: yesمجلة العلوم و آفاق المعارف, 2023
Talking about digital text or digital literature is a controversial conversation because of the intellectual differences and conflicts that the topic carries, and a great controversy taking place in the critical and literary arena.
imane hammamdji, Kaira bendahoua
doaj   +1 more source

Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird   +9 more
wiley   +1 more source

Unnatural Narratives

open access: yesLetras, 2017
A critique is developed for unnatural narratives, which respond to a new narratological schema understood in anti-mimetic terms. The main characteristics of these narratives are described in relation to concepts such as reader, time or narration ...
Roy Alfaro Vargas
doaj   +1 more source

Blood RNA Biomarker Signatures for Early Diagnosis and Prognosis in Ischemic and Hemorrhagic Stroke: The IBIS‐CT1 Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the expression of nine blood RNA biomarkers in a clinical trial based on genes previously identified in an experimental monkey model of stroke for diagnosis feasibility and prognostication. Methods IBIS‐CT1 was a prospective longitudinal study enrolling patients with ischemic stroke (IS) or intracerebral hemorrhage (ICH ...
Salomé Retailleau   +11 more
wiley   +1 more source

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