Results 171 to 180 of about 2,425,921 (247)

SARS‐CoV‐2 nucleocapsid protein variants have differential RNA chaperone activity

open access: yesThe FEBS Journal, EarlyView.
The SARS‐CoV‐2 nucleocapsid (N) protein facilitates RNA annealing through its RBD–IDR2–CTD region, identifying it as a functional RNA chaperone. The Omicron BA.5 variant shows reduced chaperone activity compared to the Wuhan wild‐type protein. Although phosphorylation has no effect on wild‐type N, phosphomimetic modification of BA.5 N restores its RNA ...
Sabrina Babl   +11 more
wiley   +1 more source

The prevalence of imposter syndrome among neurosurgeons in Europe: An EANS YNC survey. [PDF]

open access: yesBrain Spine
Zoia C   +20 more
europepmc   +1 more source

Functional divergence of protein kinase A regulatory subunit Iβ variants: the importance of N3A motifs in PKA regulation

open access: yesThe FEBS Journal, EarlyView.
The regulatory subunit RIβ of protein kinase A occurs in two variants that differ at residue 268 (A268 versus R268). This seemingly small substitution significantly changes cAMP sensitivity, basal kinase activity, and the dynamic behavior of the regulatory domains.
Maximilian Wallbott   +6 more
wiley   +1 more source

Women Leading Otherwise? Rethinking Leadership Configurations in the Music Industry Through Keychange

open access: yesGender, Work &Organization, EarlyView.
ABSTRACT Women continue to face systemic barriers to exercising leadership in the music industry. This article critically examines Keychange, a transnational initiative that seeks to transform the industry through talent development advocacy and leadership training for women and gender‐diverse individuals. Drawing on participant interviews and situated
Magkou Matina   +2 more
wiley   +1 more source

Meropenem‐Heparin Lock Therapy for Ochrobactrum intermedium Catheter‐Related Bloodstream Infection in a Pediatric Hemodialysis Patient: A Case Report and Literature Review

open access: yesHemodialysis International, EarlyView.
ABSTRACT Background In pediatric hemodialysis patients with exhausted vascular access, managing rare pathogens like Ochrobactrum intermedium is challenging, often posing a dilemma between catheter removal and salvage attempts. There are few reports on the supported viability of meropenem‐heparin lock therapy for this purpose in pediatric patients. Case
Mônica Cristina Dutra Rodrigues   +4 more
wiley   +1 more source

Saudi Women's Experiences of Sexual and Relational Changes During the Menopause Transition

open access: yesJournal of Advanced Nursing, EarlyView.
ABSTRACT Objectives This study aims to understand Saudi women's experiences of sexual and relational changes during the menopause transition. Design A qualitative, Interpretative Phenomenological Analysis study. Methods Sixteen Saudi women aged 45–57 who had experienced natural menopause transition were purposively selected and interviewed using semi ...
Samar Alotaibi   +2 more
wiley   +1 more source

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