Results 61 to 70 of about 2,855 (268)
Advanced Science, EarlyView.This review examines emerging combination immunotherapy strategies tailored to distinct tumor microenvironments and highlights next‐generation biomarkers that guide response prediction and treatment personalization. It integrates lessons from unsuccessful trials, addresses toxicity challenges, and outlines approaches for early biomarker discovery and ...
Asmita Pandey +6 more
wiley +1 more source
A DESCRIPTIVE CORRELATIONAL STUDY TO ASSESS THE IMPACT OF IMPOSTER SYNDROME ON BURNOUT AMONG CURRENTLY WORKING EMPLOYEES [PDF]
, 2023 Prachi Arya and Sheetal Panwar Gyanendri Tomar
openalex +1 more source
G3BP1 Succinylation at K413 is Critical for Cardiac Function by Modulating PI3K‐AKT‐mTOR Signal Axis
Advanced Science, EarlyView.Schematic illustrating the impact of G3BP1 succinylation at K413 on cardiac function. In the healthy human heart, G3BP1 succinylation maintains homeostatic mTOR signaling. In patients with dilated cardiomyopathy (DCM) and heart failure (HF), G3BP1 de‐succinylation induces RagA expression and disrupts the binding of the TSC1/2 complex, leading to the ...
Yuan Zhang +9 more
wiley +1 more source
Jumping Into The Deep: Imposter Syndrome, Defining Success and the New Librarian
Partnership: The Canadian Journal of Library and Information Practice and Research, 2017 This article is adapted from a presentation given at the Ontario Library Association Super Conference, held in Toronto, Ontario, February 1-4, 2017.
Sajni Lacey, Melanie Parlette-Stewart
doaj +1 more source
Generation of CCR4/CD7 Bispecific CAR‐T Cells Resistant to Fratricide and Exhaustion
Advanced Science, EarlyView.The applications of CAR T‐cell therapy in T‐cell malignancies face limitations such as fratricide, effector‐cell exhaustion, and antigen‐escape. Herein, we developed fratricide‐ and exhaustion‐resistant CAR‐T cells that targeted CCR4 and CD7 simultaneously, with optional EGFRt safety switch. Additionally, scRNA‐seq unveiled new molecular targets, which
Sile Li +10 more
wiley +1 more source
Advanced Science, EarlyView.This study reports the development of a fully humanized bispecific T cell engager targeting IL13RA2, a tumor‐associated antigen enriched in glioblastoma. This off‐the‐shelf immunotherapy drives potent, antigen‐dependent T cell activation and tumor killing, and prolongs survival in experimental GBM and other solid tumors models without detectable off ...
Joseph T. Duffy +16 more
wiley +1 more source
VoicesImposter syndrome describes a phenomenon where individuals undervalue their competence by attributing successes to external factors. The experience encompasses feelings of anxiety and shame, leading individuals to perceive themselves as frauds who do not
Jessie Ku, Rina Tabuchi
doaj +1 more source
Doctoral Student Research Alliance: Unexpected Challenges in Group Formation
Journal of Scholarly Engagement, 2020 The purpose of this reflective practice is to explore the unexpected difficulty experienced by two student members, Tara and John, and their faculty mentor of the fledgling Doctoral Student Research Alliance (DSRA) at a university in the ...
Tara Chavez +2 more
doaj +1 more source
Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing
Advanced Science, EarlyView.Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale +6 more
wiley +1 more source
روانشناسی بالینی و شخصیت, 2007 This study examined the simple and multiple relationships of defensive self presentation tactics with imposter syndrome in graduate students of Shahid Chamran University (Ahvaz- Iran).
M. Shahani-Yeilaghi, S. Basaknejad
doaj