Results 91 to 100 of about 124,033 (325)

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Stereotype of Poor Peasants of Dnieper Ukraine in the Second Half of the 19th and Early 20th Centuries: Between Ideas and Reality

Studia Historiae Oeconomicae
In the article, the author analyzes the transformations of the stereotype of peasant poverty of Dnieper Ukraine[1] in the second half of the 19th and early 20th centuries; examines the spaces of its formation and the image of the reality of peasant ...
Viktoriia Voloshenko
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Findings of the International Subarachnoid Aneurysm Trial and the National Study of Subarachnoid Haemorrhage in context.

, 2007
Concern has been expressed about the applicability of the findings of the International Subarachnoid Aneurysm Trial (ISAT) with respect to the relative effects on outcome of coiling and clipping.
Browne, JP, Copley, L, Gholkar, A, Kirkpatrick, PJ, Langham, J, Lindsay, KW, Molyneux, AJ, Reeves, BC, Shaw, D   +8 more
core   +1 more source

Terrestrial molluscs of Pemba Island, Zanzibar, Tanzania, and its status as an "oceanic" island [PDF]

, 2010
Pemba is thought to have had a longer and/or stronger history of isolation than its better-known counterpart, Unguja. The extent to which the biota support this hypothesis of greater oceanicity have been debated.
Rowson, Ben, Warren, Ben, Ngereza, Christine   +2 more
core   +3 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Hydrological degradation of automorphic soils in agricultural landscapes

Бюллетень Почвенного института им. В.В. Докучаева, 2012
The impoverishment of physical and water properties resulted from the use in agriculture for a long period of time is exemplified by soddy-podzolic, gray soils and chernozems.
G. S. Bazykina
doaj   +1 more source

Assessing the impoverishment effects of out-of-pocket healthcare payments prior to the uptake of the national health insurance scheme in Ghana

BMC International Health and Human Rights, 2017
BackgroundThere is a global concern regarding how households could be protected from relatively large healthcare payments which are a major limitation to accessing healthcare.
J. Akazili, J. Ataguba, E. Kanmiki, J. Gyapong, O. Sankoh, A. Oduro, D. Mcintyre   +6 more
semanticscholar   +1 more source

Towards performance measurement in reconstructive surgery: a multicentre pilot study of free and pedicled flap procedures.

, 2006
OBJECTIVES: To pilot the acceptability and feasibility of clinical audit in free and pedicled flap reconstruction. To establish a baseline flap failure rate in participating units, so that a sample size calculation could be performed for future national ...
Browne, JP, Cole, RP
core   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source