Results 111 to 120 of about 124,033 (325)

Measuring financial protection in health [PDF]

Health systems are not just about improving health: good ones also ensure that people are protected from the financial consequences of receiving medical care. Anecdotal evidence suggests health systems often perform badly in this respect, apparently with
Wagstaff, Adam
core  

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

30 years of hay meadow succession without fertilization: how does it affect soil and avifauna groups? [PDF]

, 2010
In the present study we investigated the effects of hay meadow succession in the brook valley system of the Drentse A Nature Reserve, in the NE of the Netherlands.
Bakker, Jan P., Bekker, Renée M., Brauckmann, Hans-Jörg, Buchwald, Rainer, Düttmann, Heinz, Vries, Yzaak de   +5 more
core  

Socioeconomic inequalities in catastrophic health expenditure and impoverishment associated with non-communicable diseases in urban Hanoi, Vietnam

International Journal for Equity in Health, 2016
BackgroundThe catastrophic health expenditure and impoverishment indices offer guidance for developing appropriate health policies and intervention programs to decrease financial inequity.
V. D. Kien, Hoang Van Minh, K. B. Giang, Amy Dao, L. Tuan, N. Ng   +5 more
semanticscholar   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Mining-induced displacement and resettlement: The case of rutile mining communities in Sierra Leone

Journal of Sustainable Mining, 2019
This study examines mining-induced displacement and resettlement (MIDR) in rutile mining communities in Sierra Leone, drawing from mining and resettlement literature and utilizing political ecology and the impoverishment risk and reconstruction (IRR ...
Sigismond A. Wilson
doaj   +1 more source

Nietzsche’s Philosophy of Mathematics [PDF]

, 1999
Nietzsche has a surprisingly significant and strikingly positive assessment of mathematics. I discuss Nietzsche's theory of the origin of mathematical practice in the division of the continuum of force, his theory of numbers, his conception of the finite
Steinhart, Eric
core  

Catastrophic health expenditure and impoverishment in Mongolia

International Journal for Equity in Health, 2016
BackgroundThe social health insurance coverage is relatively high in Mongolia; however, escalation of out-of-pocket payments for health care, which reached 41 % of the total health expenditure in 2011, is a policy concern.
Javkhlanbayar Dorjdagva, E. Batbaatar, M. Svensson, B. Dorjsuren, J. Kauhanen   +4 more
semanticscholar   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source