Results 101 to 110 of about 133,631 (312)

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

open access: yesFEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin   +12 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

open access: yesAging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey   +12 more
wiley   +1 more source

ENERGY EFFICIENT DESALINATOR

open access: yesВестник Дагестанского государственного технического университета: Технические науки, 2018
. Objectives The aim of the research was the development of an ultrasonic generator of technological design with a wide frequency range of output voltage.
Nikolaj V. Bekrenev, Dmitriy Yu. Lukov
doaj   +1 more source

In situ CCVD synthesis of carbon nanotubes within a commercial ceramic foam [PDF]

open access: yes, 2005
Consolidated nanocomposite foams containing a large quantity of carbon nanotubes (CNTs) within millimetre-sized pores are prepared for the first time.
Cordier, Anne   +4 more
core   +5 more sources

Remote Monitoring in Myasthenia Gravis: Exploring Symptom Variability

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is a rare, autoimmune disorder characterized by fluctuating muscle weakness and potential life‐threatening crises. While continuous specialized care is essential, access barriers often delay timely interventions. To address this, we developed MyaLink, a telemedical platform for MG patients.
Maike Stein   +13 more
wiley   +1 more source

Low Cost, Lightweight Gravity Coring and Improved Epoxy Impregnation Applied to Laminated Maar Sediment in Vietnam

open access: yesGeosciences, 2018
In response to the need for lightweight and affordable sediment coring and high-resolution structural documentation of unconsolidated sediment, we developed economical and fast methods for (i) recovering short sediment cores with undisturbed topmost ...
Jan P. Schimmelmann   +3 more
doaj   +1 more source

Partial Discharge in Electronic Equipments [PDF]

open access: yes, 2009
Tato disertační práce se věnuje studiu částečných výbojů (PD) způsobených poklesem spolehlivosti a životnosti elektronických zařízení a systémů. Diagnostika PD je dnes známá metoda pro vysoké napětí u vysoko-výkonných zařízení.
Mammadov, Anar
core  

Ammonia borane-based nanocomposites as solid state hydrogen stores for portable power applications [PDF]

open access: yes, 2018
Ammonia borane (AB) based nanocomposites have been investigated with the aim of developing a promising solid-state hydrogen store that complies with the requirements of a modular polymer electrolyte membrane fuel cell (PEM FC) in a portable power pack ...
Bielewski, Marek   +4 more
core   +1 more source

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito   +14 more
wiley   +1 more source

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