Results 121 to 130 of about 1,784,267 (382)
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Oberlin Perfectionism and Its Edwardsean Origins
, 1996 An impression has very generally prevailed, wrote James Harris Fairchild toward the end of his twenty-three-year presidency of Oberlin College, that the theological views unleashed at Oberlin College by the late Rev.
Guelzo, Allen C.
core
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
[Review of] Ji, Meng (ed) (2016). Empirical Translation Studies. Interdisciplinary Methodologies Explored. Sheffield (UK)/Bristol (USA): Equinox, pp. 238, £17.52. ISBN: 9781781790496 (hardback) [PDF]
, 2016 The back cover of this book describes it as “a practical study guide to postgraduate and research students of applied translation studies.” This might give the impression that the volume is a textbook, which it is not. Rather, the book is a collection of
Buysschaert, Joost
core +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Negative Stereotypes and Willingness to Change Them: Testing Theories of Discrimination in South Africa [PDF]
This paper proposes a new test to distinguish between the two leading theories of discrimination: preference versus information. Discrimination based on preferences occurs when people behave as if they refuse to change their stereotypes about the ...
Aguero, Jorge M.
core +3 more sources
Ultrasonic angle beam standard reflector [PDF]
, 1985 A method that provides an impression profile in a reference standard material utilized in inspecting critically stressed components with pulsed ultrasound is described. A die stamp having an I letter is used to impress the surface of a reference material.
Berry, R. F., Jr.
core +1 more source
Professional Life of Information System Graduates : Impressions and Experiences
, 2020 Georg Disterer
openalex +2 more sources