Results 131 to 140 of about 393,960 (308)
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
POSSIBILITIES AND LIMITATIONS OF DIGITAL IMPRESSIONS IN COMPLETE REMOVABLE DENTURE PROSTHETICS
Relevance. The fabrication of complete dentures for edentulous jaws is a cornerstone of prosthetic dentistry, and retention is a critical factor for clinical success.
O.V. Shemetov
doaj +1 more source
Spatial impression in multichannel surround sound systems [PDF]
Spatial impression in both concert halls and reproduced sound has been identified as an important attribute of the listening experience. In this study, the synthesis and objective measurement of spatial impression in reproduced sound is examined.A novel,
Hirst, JM
core
Impression management en concurso de acreedores: Un análisis de la información narrativa en empresas cotizadas [PDF]
Managers tend to use opportunistically corporate narrative disclosure when financial performance is poor. However, there is little research on impression management in situations of extreme distress, such as bankruptcy.
Moreno, Alonso +4 more
core +1 more source
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Expressed Impressions of Impressed Expressions [PDF]
openaire +1 more source
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source

