Results 131 to 140 of about 515,173 (355)
Taurine promotes glucagon‐like peptide‐1 secretion in enteroendocrine L cells
Taurine, a sulfur‐containing amino acid, is likely taken up by enteroendocrine L cells via the taurine transporter. This process increases the levels of cytosolic ATP. The increase in intracellular Ca2+ concentrations and glucagon‐like peptide‐1 secretion through membrane depolarization is caused by the closure of ATP‐sensitive potassium channels ...
Yuri Osuga+6 more
wiley +1 more source
Making tau amyloid models in vitro: a crucial and underestimated challenge
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
The Age of the Crusades. James M. LudlowThe Latin Kingdom of Jerusalem. 1099 to 1291 A. D.C. R. ConderL'Islam, Impressions et Études. Henry de CastriesDer Geisteskampf des Christentums gegen den Islam, bis zur Zeit der Kreuzzüge. Adolf Keller [PDF]
Oliver J. Thatcher
openalex +1 more source
The S1025 peptide is the major antidote to the YrzI toxin, which we renamed here as SpyT (Small Peptide YrzI Toxin) and SpyA (Small Peptide YrzI Antitoxin) (1). Degradation of the toxin–antitoxin spyTA mRNA, either by a translation‐dependent cleavage by the endoribonuclease Rae1 (2) or by direct attack by 3′‐exoribonucleases (3), also contributes to ...
Laetitia Gilet+4 more
wiley +1 more source
Jiamin Li,1,2 Zhenchao Zhong,1,2 Lei Mo1,2 1Key Laboratory of Brain, Cognition and Education Sciences, Ministry of Education, Guangzhou 510631, People’s Republic of China; 2School of Psychology, Center for Studies of Psychological Application ...
Li J, Zhong Z, Mo L
doaj
α2 → 8 polysialic acid elicits poor immunogenicity. Small‐angle scattering shows a supramolecular structure with parallel‐chain binding, although in different forms at μm and mm calcium. The major histocompatibility complex requires molecular weights around 2000 Da to produce antibodies, and 2000 Da polysialic oligomers will bind in these structures ...
Kenneth A. Rubinson
wiley +1 more source
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma+8 more
wiley +1 more source
Construction and Analysis of Impression Caption Dataset for Environmental Sounds [PDF]
Some datasets with the described content and order of occurrence of sounds have been released for conversion between environmental sound and text. However, there are very few texts that include information on the impressions humans feel, such as "sharp" and "gorgeous," when they hear environmental sounds.
arxiv
Compatriot and foreigner: A study of impression formation in three countries. [PDF]
Jerome S. Bruner, Howard V. Perlmutter
openalex +1 more source
The power of microRNA regulation—insights into immunity and metabolism
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto+2 more
wiley +1 more source