Results 131 to 140 of about 1,484,214 (321)

Archaeal protein containing domain of unknown function 2193 undergoes oligomeric reconfiguration upon iron–sulfur cluster binding

open access: yesFEBS Letters, EarlyView.
This work presents the characterization of MvoDUF2193, a Methanococcus voltae (Mvo) protein from the domain of unknown function (DUF) 2193 family. We demonstrate that MvoDUF2193 binds a single [4Fe–4S] cluster per subunit and that cluster occupancy regulates the transition from an apo tetramer to a [4Fe–4S] monomeric form. This structural transition is
Emily M. Dieter   +8 more
wiley   +1 more source

Everything\u27s Zen: Review of The Body Artist by Don DeLillo [PDF]

open access: yes, 2001
Reading the beginning of Don DeLillo’s latest book feels like groping through a room in the blinding morning light before you’ve had a cup of coffee.
Kuhlman, Martha
core   +1 more source

ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling

open access: yesFEBS Letters, EarlyView.
In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li   +3 more
wiley   +1 more source

Oberlin Perfectionism and Its Edwardsean Origins

open access: yes, 1996
An impression has very generally prevailed, wrote James Harris Fairchild toward the end of his twenty-three-year presidency of Oberlin College, that the theological views unleashed at Oberlin College by the late Rev.
Guelzo, Allen C.
core  

Digital Sculpting for Historical Representation: Neville Tomb Case Study [PDF]

open access: yes, 2011
Despite digital 3D poly-modelling applications providing a common and powerful tool-set for archaeological, architectural and historical visualisation over recent years, digital deformation sculpting tools are little used at present within the area of ...
Fitzpatrick, Frank, Unver, Ertu
core  

Structural arrangement of emotional experience of family relations of adolescents

open access: yesУченые записки Казанского университета: Серия Гуманитарные науки, 2018
Adolescence is the most important stage of human development. The purpose of the study is to investigate in detail the features of structural arrangement of the experience of family relations in adolescents within the child-parent subsystem.
L.R. Fachrutdinova
doaj  

Neutrophil deficiency increases T cell numbers at the site of tissue injury in mice

open access: yesFEBS Letters, EarlyView.
In wild‐type mice, injury or acute inflammation induces neutrophil influx followed by macrophage accumulation. Mcl1ΔMyelo (neutrophil‐deficient) mice lack neutrophils, and in response to muscle injury show fewer macrophages and exhibit strikingly elevated T‐cell numbers, primarily non‐conventional “double‐negative” (DN) αβ and γδ T cells.
Hajnalka Halász   +6 more
wiley   +1 more source

Functional role and folding properties of the glucan‐binding domain of oral bacterial glucansucrase

open access: yesFEBS Letters, EarlyView.
The role of the glucan‐binding domain in Streptococcus sobrinus glucansucrase was examined, focusing on its impact on enzymatic activity, dextran binding, and structural stability of deletion mutants and a circularly permuted protein. Our research revealed that glucosyl transfer efficiency is linked to cooperative interdomain folding.
Hideyuki Komatsu   +5 more
wiley   +1 more source

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