Results 241 to 250 of about 1,570,145 (331)

Diagnostic Value of Conjunctival Impression Cytology and Nelson Grading in Evaluating Dry Eye Disease in Ankylosing Spondylitis. [PDF]

Medicina (Kaunas)
Yildirim T, Dikci S, Akatli AN.
europepmc   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

A Randomized Controlled Trial to Evaluate and Compare the Vertical Marginal Fit of Monolithic Zirconia Crowns Obtained Using Intraoral Scanning vs Monophase Impression Technique: An <i>In Vivo</i> Study.

J Pharm Bioallied Sci
Kaknale RN, Gupta RK, Bhargava A, Dua B, Goyat MK, Lakhe MA.   +5 more
europepmc   +1 more source

Comparing impression techniques in the prosthodontic treatment for edentulous patients: a 3D finite element analysis. [PDF]

J Adv Prosthodont
Bondoc MDZ, Kim ME, Lim YJ, Kim MJ, Kwon HB.   +4 more
europepmc   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Comparative Performance of Visual Inspection with Acetic Acid and Colposcopy for Detection of Cervical Precancer in Women with High-Risk Human Papillomavirus Infection: A Cross-Sectional Study. [PDF]

Cancer Control
Kuljarusnont S, Karnchanabanyong W, Ruengkhachorn I, Ularnwong M, Ittiamornlert P, Hanamornroongruang S.   +5 more
europepmc   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Simulation of the Periodontal Ligament in Dental Materials Research: A CAD/CAM-Based Method for PDL Modeling. [PDF]

J Funct Biomater
Kosewski P, Kosewski J, Mielczarek A.
europepmc   +1 more source

Impressions

Journal of the California Dental Association, 2022
openaire   +1 more source