Results 91 to 100 of about 8,744,050 (279)

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

How the Adoption of Impression Management Goals Alters Impression Formation

open access: yes, 2010
Five experiments ( N = 390) tested the hypothesis that adopting an impression management goal leads the impression manager to view an interaction partner as having less of the trait he or she is attempting to express.
Bryan Gibson, Elizabeth M. Poposki
core   +1 more source

Importance of impression management of referees: a qualitative study

open access: yesRevista Brasileira de Futsal e Futebol, 2022
Referees are major stakeholders in any game as their role is to keep both fairness and justice intact in the game, but despite all their effort and contributions, referees often face criticism.
Mücahit Fişne, Ali Hasaan
doaj  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Corporate profit and impression management in developing markets [PDF]

open access: yes, 2011
In this study, we examine how organisations in Fiji communicate or legitimise their profit. We base the need for understanding this phenomenon on the following premise.
Finau, Glen   +2 more
core   +2 more sources

Accounting Narratives and Impression Management [PDF]

open access: yes, 2013
This chapter focuses on impression management in accounting communication. Impression management entails the construction of an impression by organisations with the intention to appeal to their audiences, including shareholders, stakeholders, the ...
Merkl-Davies, Doris M., Brennan, Niamh
core   +1 more source

Impression management within the recruitment interview: Narratives of employees at a South African higher education institution

open access: yesSA Journal of Industrial Psychology, 2018
Orientation: Job interviews remain a popular platform on which organisations source talent. Interviewees seek to make an impression in interviews to influence the decision to be hired.
Vuyelwa Dondolo, Willie T. Chinyamurindi
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Diversity as Impression Management [PDF]

open access: yes, 2020
In recent years, increasing scrutiny has been placed on groups and organizations and their levels of diversity. Because groups and organizations have incentives to avoid negative scrutiny and often engage in attempts to manage impressions around ...
Chang, Edward H, Chang, Edward
core  

Home - About - Disclaimer - Privacy