Results 81 to 90 of about 29,339 (237)

Comparison of plasma cell bone marrow counts by different methods in patients diagnosed with plasma cell disorders

Hematology, Transfusion and Cell Therapy
Introduction: Plasma cell quantification in bone marrow is important for diagnosis, prognosis, and treatment of plasma cell diseases. It can be performed by several methods such as aspiration, imprint and flow cytometry, and biopsy.
Claudia Monteiro, Paulo Campregher, Denise Pasqualin, Nydia Bacal, Liliana Suganuma, Elvira Velloso   +5 more
doaj   +1 more source

Borophene: Crucial Challenges and the Way Forward

Advanced Science, EarlyView.
This review explores the challenges and progress in borophene research, focusing on synthesis strategies, structural properties, and potential applications. It highlights key experimental breakthroughs, discusses theoretical insights into borophene's unique features, and addresses pathways for overcoming stability and scalability issues.
Zhixuan Li, Jeyaraman Sankar, Prashant Kumar, Ajayan Vinu   +3 more
wiley   +1 more source

Periodontitis Induces B Cell‐Macrophage Crosstalk to Exacerbate Glucose Dysregulation in Obesity

Advanced Science, EarlyView.
In obesity, periodontitis exacerbates hyperglycemia and exhibits a liver‐centric preference for glucose regulation. This occurs through a periodontitis‐driven circuit between pathogenic B cells and hepatic macrophages. Their reciprocal expansion, orchestrated by the NLRP3/IL‐18 signaling pathway, amplifies metabolic inflammation and disrupts glucose ...
Wen‐Zhen Lin, Lu‐Jun Zhou, Hui‐Lin Ye, Ting Liu, Bo‐Yan Chen, Xue‐Bing Bai, Jun Zhang, Lan Bai, Lin‐Juan Du, Yuan Liu, Yong‐Li Wang, Hong Zhu, Yu‐Lin Li, Shuo Xu, Xiao‐Qian Meng, Guo‐Cai Tian, Yan Liu, Wu‐Chang Zhang, Ya‐Qin Zhu, Sheng‐Zhong Duan   +19 more
wiley   +1 more source

NanoLoop: A Deep Learning Framework Leveraging Nanopore Sequencing for Chromatin Loop Prediction

Advanced Science, EarlyView.
Chromatin loops are central to gene regulation and 3D genome organization. Leveraging Nanopore sequencing's ability to jointly capture DNA sequence and methylation, we present NanoLoop, the first framework for genome‐wide chromatin loop prediction using Nanopore data.
Wenjie Huang, Li Tang, Matthew C. Hill, Yonghao Zhang, Jun Xie, Min Li   +5 more
wiley   +1 more source

Machine Learning‐Enhanced Analysis of Exosomal Surface Sialic Acid Using Surface‐Enhanced Raman Spectroscopy for Ovarian Cancer Diagnosis and Therapeutic Monitoring

Advanced Science, EarlyView.
Machine learning‐assisted surface‐enhanced Raman spectroscopy analysis of exosomal sialic acid for ovarian cancer diagnosis, as well as independent monitoring of exosomal sialic acid expression levels across different treatment periods, reveals a potential correlation with treatment response.
Lili Cong, Jiaqi Wang, Sijun Huang, Xiaxia Man, Yi Guo, Shuping Xu, Songling Zhang   +6 more
wiley   +1 more source

Nanoimprinted DMD Electrodes Enabling Bidirectional Viewing OLEDs With Quasi Lambertian Emission

Advanced Science, EarlyView.
We present a dual‐approach strategy for high‐performance bidirectional‐viewing OLEDs, combining enhanced cavity resonance with a nanoimprinted dielectric/metal/dielectric (DMD) electrode. This bidirectional viewing OLED presents an 89.7% enhanced electrode transmittance, a balanced bidirectional emission ratio with 67.3% total brightness increase, as ...
Ningning Song, Ningning Liang, Xinghao Guo, Ruixiang Chen, Xia Xin, Yiming Chen, Ruiqi Tian, Tianrui Zhai   +7 more
wiley   +1 more source

miR‐135a‐5p Is a Promising Target to Prevent the Glomerulosclerosis Associated with Podocyte Developmental Toxicity in Offspring Induced by Prenatal Dexamethasone Exposure

Advanced Science, EarlyView.
Prenatal dexamethasone exposure (PDE) programs persistent podocyte developmental injury and adult glomerulosclerosis. Mechanistically, glucocorticoid receptor (GR) binds the miR‐135a‐5p promoter and recruits the histone acetyltransferase p300, increasing promoter histone acetylation and sustaining miR‐135a‐5p expression. Elevated miR‐135a‐5p suppresses
Xiaoqi Zhao, Haiyun Chen, Yanan Zhu, Zhiping Xia, Hangyuan He, Yutang Liu, Tianshu Yang, Hui Wang, Ying Ao   +8 more
wiley   +1 more source

Quantitative Stain Mapping in X‐Ray Virtual Histology

Advanced Science, EarlyView.
Virtual histology promises 3D tissue examination without physical sectioning, yet has lacked the tissue‐specificity of conventional pathology. This work demonstrates the first quantitative three‐dimensional stain mapping at histologically relevant resolution, separating contrast agent from tissue to reveal cellular features such as nuclei. The approach
Dominik John, David M. Paganin, Marie‐Christine Zdora, Lisa Marie Petzold, Patrick Ilg, Junan Chen, Sara Baggio, Johannes B. Thalhammer, Sami Wirtensohn, Julian Moosmann, Jörg U. Hammel, Felix Beckmann, Samantha J. Alloo, Jannis N. Ahlers, Madleen Busse, Julia Herzen, Kaye S. Morgan   +16 more
wiley   +1 more source

MVP Inhibits Influenza A Virus‐Induced Ferroptosis by Targeting IRF1 and Increasing FSP1 Activity

Advanced Science, EarlyView.
During IAV infection, MVP inhibits IRF1 polyubiquitination, thereby relieving IRF1‐mediated transcriptional inhibition of FSP1. Consequently, this leads to an upregulation of FSP1 expression, thereby reinforcing the inhibition of ferroptosis. In addition, the MVP can promote myristoylation and ubiquitination of FSP1, enabling its membrane localization ...
Yingbo Chen, Paili Lin, Yongfang Xia, Zhiqiang Liu, Zilu Cheng, Qingmei Zhu, Shiqi Wan, Xiaoyu Chen, Haiyan Bao, Renbo Qiao, Gechang Zhong, Ying Zhu, Shi Liu   +12 more
wiley   +1 more source

3D‐Printed Ion‐Conductive Hydrogels with Tunable Mechanical–Electrical Properties for Multimodal Sign Language Recognition

Advanced Science, EarlyView.
This work successfully fabricated ion‐conductive hydrogels with low hysteresis and high conductivity using 3D printing technology. By adjusting the component ratios, the properties of the hydrogels can be tuned to meet diverse sensing requirements. Finally, a multimodal sensing sign language recognition system was constructed based on this hydrogel ...
Quan Hu, Longya Xiao, Peiqi Zhang, Qiurui Zhang, Guangsen Liu, Xinglin Qin, Zhuhui Yin, Xian Li, Yuling Wang, Hongjie Jiang   +9 more
wiley   +1 more source