Results 81 to 90 of about 22,120,804 (300)

Improving Customer Satisfaction: Changes as a Result of Customer Value Discovery

Evidence Based Library and Information Practice, 2008
Objective: To identify Gold Standard Services for customers in an academic library and determine whether interventions following the identification of customer value increased student satisfaction.Methods: “Customer Discovery Workshops” were undertaken ...
Mike Berrington, Susan McKnight
doaj  

Particle Swarm Optimization Support Vector Machine-Based Grounding Fault Detection Method in Distribution Network

Algorithms
With the present fault detection method for low-voltage distribution networks, it is difficult to detect single-phase grounding faults under complex working conditions. In this paper, a particle swarm optimization (PSO) support vector machine (SVM)-based
Zhongqin Xiong, Shichang Huang, Shen Ren, Yutong Lin, Zewen Li, Dongyu Li, Fangming Deng   +6 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

VALUE CREATION AND RESOURCE-BASED VIEW

, 2010
A PRESENTATION OF LINKAGES BETWEEN VALUE CREATION STUDIES AND RESOURCE-BASED ...
SCIARELLI, MAURO
core  

Deep learning network enhances imaging quality of low-b-value diffusion–weighted imaging and improves lesion detection in prostate cancer

BMC Cancer
Diffusion-weighted imaging with higher b-value improves detection rate for prostate cancer lesions. However, obtaining high b-value DWI requires more advanced hardware and software configuration. Here we use a novel deep learning network, NAFNet, to generate a deep learning reconstructed (DLR1500) images from 800 b-value to mimic 1500 b-value images ...
Zheng Liu, Wei-jie Gu, Fang-ning Wan, Zhang-zhe Chen, Yun-yi Kong, Xiao-hang Liu, Ding-wei Ye, Bo Dai   +7 more
openaire   +3 more sources

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Valuing the Historic Environment: a critical review of existing approaches to social value [PDF]

, 2015
Through a critical review of existing research, this report examines current knowledge and understanding of social value. Encompassing the significance of the historic environment to contemporary communities, social value relates to people’s sense ...
Jones, Sian, Leech, Steven, Leech, S., Jones, S.   +3 more
core  

Evaluating the Diagnostic Accuracy of Point-of-Care CXCL13 Measurements for Lyme Neuroborreliosis

Diagnostics
Background: Measurements of the B-cell attracting chemokine CXCL13 in cerebrospinal fluid (CSF) has become increasingly popular in the diagnostic work-up for Lyme neuroborreliosis (LNB).
Lasse Fjordside, Mathilde Ørbæk, Thomas Bryrup, Louise Helvig Kaas, Alex Christian Yde Nielsen, Nikolai Søren Kirkby, Helene Mens, Anne-Mette Lebech   +7 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source