Results 111 to 120 of about 6,993,900 (238)
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
The differential evolution algorithm as applied to array antennas and imaging
, 2008 The application of the differential evolution method in two important areas of applied electromagnetics is discussed in this chapter. The first one refers to the synthesis and design of array antennas, for which differential evolution, as well as other ...
PASTORINO, MATTEO +2 more
core +1 more source
, 2012 A differential evolution (DE) algorithm aided iterative channel estimation and turbo multi-user detection (MUD) scheme is proposed for multi-user multi-input multiple-output aided orthogonal frequency-division multiplexing/spacedivision multiple-access ...
Chen, Sheng +3 more
core +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Electromagnetic Device Optimization using Improved Differential Evolution Methods
, 2006 Recently, evolutionary algorithms (e.g. genetic algorithms, evolutionary programming, and evolution strategies) have proven to be useful tools for the optimization of difficult problems in electromagnetics.
L. dos Santos Coelho +3 more
core +1 more source
Pattern Synthesis of Linear Antenna Array Using Improved Differential Evolution Algorithm with SPS Framework. [PDF]
Sensors (Basel), 2020 Zhang R, Zhang Y, Sun J, Li Q.
europepmc +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Vehicle Routing Problem with Time Windows Based on Improved Differential Evolution Algorithm
, 2009 The paper redefines differential evolution algorithm's mutation and crossover operations for dealing with discrete problems effectively, and it also introduces a variation mechanism to avoid individual stagnation. Then the improved differential evolution
Jian-Wen Wu, Chuan He, Yuan-Biao Zhang
core +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source