Results 111 to 120 of about 1,252,934 (262)

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Efficiency and Productivity of Farmers in Nigeria: A Study of Rice Farmers in North Central Nigeria

This study contributes to the agricultural productivity literature in developing countries and Nigeria especially by quantifying the level of efficiency for sample of rice farmers from North Central Zone of Nigeria.
Ogundele, O.O., Oyewusi, B.O., Okoruwa, Victor O.   +2 more
core  

Developments in mechanized farming equipment: Cotton harvester further improved toward full efficiency

California Agriculture, 1948
Few California farmers grow cotton exclusively.
J Fairbank
doaj  

Improved efficiency for cross-arm comparisons via platform designs. [PDF]

Biostatistics, 2023
Huang TJ, Luedtke A, AMP INVESTIGATOR GROUP.   +2 more
europepmc   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

EFFICIENCY IN COMMUNITY DEVELPOMENT LOAN FUNDS

We study the efficiency of Community Development Loan Funds (CDLFs) in the U.S.A. between 2002 and 2005. We find that the largest CDLFs tend to be most efficient and that efficiency decreases with age and the proportion of minority representation on the ...
Naanwaab, Cephas, Hartarska, Valentina M.   +1 more
core  

A novel solar panel cleaning system for improved efficiency

Unconventional Resources
Dust accumulation on photovoltaic module surfaces hinders sunlight penetration, causing overheating, degradation, and disposal issues that plague the solar energy industry.
Hicham Oufettoul, Othman Oubraik, Ibtihal Ait Abdelmoula, Saad Motahhir, Badre EL Majid   +4 more
doaj   +1 more source

Steering-by-leaning facilitates intuitive movement control and improved efficiency in manual wheelchairs. [PDF]

J Neuroeng Rehabil, 2023
Togni R, Zemp R, Kirch P, Plüss S, Vegter RJK, Taylor WR.   +5 more
europepmc   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source