Results 151 to 160 of about 3,421,975 (283)

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Tunable Response of Silica-Gold Nanoparticles for Improved Efficiency in Photothermal Therapy. [PDF]

Nanomaterials (Basel)
Motilla-Montes JR, Ruvalcaba-Ontiveros RI, Murillo-Ramírez JG, Medina-Vázquez JA, Esparza-Ponce HE.   +4 more
europepmc   +1 more source

Co-production of pigment and high value-added bacterial nanocellulose from Suaeda salsa biomass with improved efficiency of enzymatic saccharification and fermentation. [PDF]

Front Bioeng Biotechnol, 2023
Tan R, Sun Q, Yan Y, Chen T, Wang Y, Li J, Guo X, Fan Z, Zhang Y, Chen L, Wu G, Wu N.   +11 more
europepmc   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Advanced blade profiles for improved efficiency in Savonius wind turbines: the aeroleaf case study. [PDF]

Sci Rep
Hosseinian SM, Mohseni M, Karimi MS.
europepmc   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Improved efficiency of the new Mirus™ system challenged by ventilatory settings-a bench study. [PDF]

J Clin Monit Comput
Albrecht F, Schirra C, Scheffler K, Volk T, Meiser A.   +4 more
europepmc   +1 more source

A capture methyl-seq protocol with improved efficiency and cost-effectiveness using pre-pooling and enzymatic conversion. [PDF]

BMC Res Notes, 2023
Hasegawa K, Nakabayashi K, Ishiwata K, Kasuga Y, Hata K, Tanaka M.   +5 more
europepmc   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Substantially improved efficiency and selectivity of carbon dioxide reduction by superior hydrated electron in microdroplet. [PDF]

Sci Adv
Ge Q, Liu Y, You W, Li Y, Wang W, Yang L, Xie L, Li K, Wang L, Ma M, Wang R, Wang J, Huang T, Wang T, Ruan X, Ji M, Zhang L.   +16 more
europepmc   +1 more source