Results 41 to 50 of about 16,708 (237)

Improved Dual-Center Particle Swarm Optimization Algorithm

Mathematics
This paper proposes an improved dual-center particle swarm optimization (IDCPSO) algorithm which can effectively improve some inherent defects of particle swarm optimization algorithms such as being prone to premature convergence and low optimization ...
Zhouxi Qin, Dazhi Pan
doaj   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

A Hybrid Artificial Neural Network and Particle Swarm Optimization algorithm for Detecting COVID-19 Patients

Kurdistan Journal of Applied Research, 2021
COVID-19, one of the most dangerous pandemics, is currently affecting humanity. COVID-19 is spreading rapidly due to its high reliability transmissibility.
Alla Ahmad Hassan, Tarik A Rashid
doaj   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Swarm intelligence–based energy efficient clustering with multihop routing protocol for sustainable wireless sensor networks

International Journal of Distributed Sensor Networks, 2020
Wireless sensor network is a hot research topic with massive applications in different domains. Generally, wireless sensor network comprises hundreds to thousands of sensor nodes, which communicate with one another by the use of radio signals.
Mohamed Elhoseny, R Sundar Rajan, Mohammad Hammoudeh, K Shankar, Omar Aldabbas   +4 more
doaj   +1 more source

Improved Adaptive Holonic Particle Swarm Optimization

Mathematical Problems in Engineering, 2019
For the first time , the Holonic Particle Swarm Optimization (HPSO ) algorithm applies multiagent theory about the improvement in the PSO algorithm and achieved good results. In order to further improve the performance of the algorithm, this paper proposes an improved Adaptive Holonic Particle Swarm Optimization (AHPSO) algorithm.
Hao Li, Hongbin Jin, Hanzhong Wang, Yanyan Ma   +3 more
openaire   +1 more source

Improving the Particle Swarm Optimizer by Function “Stretching” [PDF]

, 2001
In this paper a new technique, named Function “Stretching”, for the alleviation of the local minima problem is proposed. The main feature of this technique is the usage of a two—stage transformation of the objective function to eliminate local minima, while preserving the global ones. Experiments indicate that combined with the Particle Swarm Optimizer
Parsopoulos, K. E., Plagianakos, V. P., Magoulas, G. B., Vrahatis, M. N.   +3 more
openaire   +2 more sources

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source