Results 211 to 220 of about 10,044,809 (291)

Systematic review and data-driven insights into CHO cell engineering for next-generation antibody production. [PDF]

MAbs
Schulz A, Munro T, Puklowski A, Slack E, Tolstrup AB, Otte K.   +5 more
europepmc   +1 more source

Frequency Modulation Capability Improvement Method of Offshore Wind Farms Based on Energy Storage Devices [PDF]

Sichao Pan, Yue Yang, Ranran An, Xiaobing Liang, Wenlong Yang, Jiancun Liu   +5 more
openalex   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Evaluation of safety and efficacy of the combination of mebeverine and sulpiride in treatment of patients with functional gastrointestinal disorders: A prospective cohort. [PDF]

J Int Med Res
El-Kassas M, Tawheed A, El Halwagy H, Ezzat R, El Fouly A, Elfert A.   +5 more
europepmc   +1 more source

Antiviral treatment in adult patients hospitalized for influenza: study protocol for a multi-center, randomized, placebo-controlled trial on the efficacy of baloxavir marboxil to reduce time to clinical improvement and the risk for severe complications (the INFLUENT trial) [PDF]

Krisztina Hosszu-Fellous, Antoine Poncet, Ana Rita Goncalves Cabecinhas, Manuel Schibler, Benjamin Meyer, Virginie Prendki, Angela Huttner, Sebastian Carballo, Mathias Pouillon, Ksenija Slankamenac, Pierre-Alexandre Bart, Enos Bernasconi, Oriol Manuel, Matteo Mombelli, Nicolas J. Mueller, Laurent Kaiser, Pauline Vetter   +16 more
openalex   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

The comparative effect between the new spider splint with conventional metal splint on improvement of hand function in patients with radial nerve injury

, 2009
Mokhtar Arazpour, Ismail Ebrahimi Takamjani, Mahmood Bahramizadeh, Karimlou Masoud, Reza Vahab Kashani, Mardani Mardani   +5 more
openalex   +1 more source

Mechanical Property Improvement of Epoxy Composites by Electrospun SiO2 Nanofibers [PDF]

Davoud Khademi, Alireza Khademi, Masoud Pour   +2 more
openalex   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Palliative Osimertinib Rechallenge Achieving Rapid Improvement in Leptomeningeal Carcinomatosis After Prior Osimertinib-Induced ILD. [PDF]

Respirol Case Rep
Nigi A, Iwamoto K, Itani H, Kondou S.
europepmc   +1 more source