Results 41 to 50 of about 74,722 (304)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

On the Characteristics of Electrical Figure of Chopped Impulse Voltage. [PDF]

open access: yes, 1956
In the previous issue authors reported on the characteristics of electrical figures obtained from four kinds of impulse voltages and showed their differences produced from wave forms.In this paper the characteristics of the same impulse voltages which ...
IKEJIRI, Tadao   +5 more
core   +1 more source

Performance Prediction of OWC Type Small Size Wave Power Device with Impulse Turbine

open access: yesJournal of Fluid Science and Technology, 2008
This paper investigates a small size wave power device with an impulse turbine installed in the breakwater near Niigata Port, Japan. The device consists of an air chamber, a turbine, a generator and pressure-relief valves.
Masami SUZUKI   +5 more
doaj   +1 more source

Developmental Traits of Impulse Control Behavior in School Children under Controlled Attention, Motor Function, and Perception

open access: yesChildren, 2021
This research surveyed the characteristics of the developmental traits of impulse control behavior in children through parent-report questionnaires.
Hsin-Yung Chen   +6 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Application of Time-Difference-of-Arrival Localization Method in Impulse System Radar and the Prospect of Application of Impulse System Radar in the Internet of Things

open access: yesIEEE Access, 2018
The impulse system radar is based on the generation, transmission, radiation, receiving, data collection, data processing, and imaging of impulse signals.
Longfei Dang, Hongchun Yang, Baohua Teng
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Impulse Characteristics of Ground Electrodes in Low Resistivity Soil

open access: yes, 2023
Soil properties have been known to be the factors that influence the ionization process in soil, which cause the impulse impedance, Zimpulse to be lower than that at steady state resistance, RDC. Many studies have established the relationship between the
Syed Abdullah, Syarifah Amanina   +3 more
core   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

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