Results 51 to 60 of about 581,049 (289)
WARS2-Associated Neuropsychiatric Phenotype in Childhood: A Case-Based Review
Annals of Indian Academy of NeurologyMitochondrial WARS2-related disorders are known to exhibit a broad phenotypic spectrum, ranging from infantile-onset epilepsy syndromes to hyperkinetic movement disorders. We report a case of an 11-year-old male who presented with tremors, dystonic falls,
Shabnam Kalita +3 more
doaj +1 more source
Development and automation of a test of impulse control in zebrafish
Frontiers in Systems Neuroscience, 2013 Deficits in impulse control (difficulties in inhibition of a pre-potent response) are fundamental to a number of psychiatric disorders, but the molecular and cellular basis is poorly understood.
Matthew O Parker +6 more
doaj +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Известия Иркутского государственного университета: Серия "Математика"Modeling the motion of a manipulation robot with a large number of degrees of freedom leads to complex nonlinear control systems of high-dimensional differential equations.
Yu. F. Dolgii, A.N. Sesekin
doaj +1 more source
Philosophy of life in successful community
Філософія освіти, 2019 Historical experience and scientific researches witness that both an individual’s life success and a country’s prosperity and the living standard of population depend not on the quality of education itself, but on its effectiveness.
Valentyn Mychailovych Pomohaibo
doaj +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Frontiers in Psychology, 2018 American football is played in a dynamic environment that places considerable demands on a player’s ability to make fast, precise reactions while controlling premature, impulsive reactions to spatial misinformation.
Theodore R. Bashore +6 more
doaj +1 more source
Optimal Exploitation of a General Renewable Natural Resource under State and Delay Constraints
Mathematics, 2020 In this work, we study an optimization problem arising in the management of a natural resource over an infinite time horizon. The resource is assumed to evolve according to a logistic stochastic differential equation.
M’hamed Gaïgi +2 more
doaj +1 more source
Performance Monitoring of Control Systems using Likelihood Methods [PDF]
, 1995 Evaluating deterioration in performance of control systems using closed loop operating data is addressed. A framework is proposed in which acceptable performance is expressed as constraints on the closed loop transfer function impulse response ...
Morari, Manfred, Tyler, Matthew L.
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